The cytotoxicity of DC0-NH2 is 1000 times that of commonly used anti-cancer drugs (such as doxorubicin). It is the effect part of ADC. It is a simplified simulation of DC1 and has better stability. DC0-NH2 can bind to the small groove of DNA, and then ade
a15:0-i15:0 PE 是一种包含两个支链的二酰基磷脂酰乙醇胺。这种化合物是非典型的TLR2-TLR1异二聚体激动剂,并具有免疫原性。它能够激活T细胞和DC的信号传导并表现出抗炎特性。此外,a15:0-i15:0 PE 能诱导TNFα和IL-6的产生,并且是A. muciniphila脂质膜的主要成分之一(约50%)。