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Anti-SLAMF6 Antibody-FITC (4Z355) 是一种 FITC-conjugated Rabbit 抗体,靶向 SLAMF6。Anti-SLAMF6 Antibody-FITC (4Z355) 可用于 FCM。
Anti-SLAMF6 Antibody-FITC (4Z355) 是一种 FITC-conjugated Rabbit 抗体,靶向 SLAMF6。Anti-SLAMF6 Antibody-FITC (4Z355) 可用于 FCM。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
25 T | ¥ 685 | 5日内发货 | |
100 T | ¥ 2,195 | 5日内发货 |
产品描述 | Anti-SLAMF6 Antibody-FITC (4Z355) is a FITC-conjugated Rabbit antibody targeting SLAMF6. Anti-SLAMF6 Antibody-FITC (4Z355) can be used in FCM. |
别名 | SLAM family member 6, SF2000, NTB-A, NTBA, Ly108, KALIb, KALI, CD352 |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 4Z355 |
交叉反应 | Human |
验证活性 | Flow cytometric analysis of Human SLAMF6(CD352) expression on human whole blood lymphocytes. Cells were stained with FITC-conjugated anti-Human SLAMF6(CD352). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
应用 | FCM |
推荐剂量 | 10 μl/Test, 0.1 mg/ml |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human Ly108/SLAMF6 (rh Ly108/SLAMF6; TMPY-01914; Q96DU3-1; Met1-Met226) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
研究背景 | SLAM family member 6, also known as Activating NK receptor, NK-T-B-antigen, NTB-A, SLAMF6, KALI and Ly18, is a single-pass type I membrane protein that belongs to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6 / Ly18 contains one Ig-like (immunoglobulin-like) domain. It is expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes. SLAMF6 / Ly18 triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors. SLAMF6 / Ly18 is a homodimer. It interacts with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP. SLAMF6 / Ly18 undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. SLAMF6 / Ly18 can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. |
偶联 | FITC |
其他可选修饰符 | Unconjugated/APC/PE |
可提供抗体种类 | 4 |
免疫原 | Recombinant Human Ly108/SLAMF6 Protein (TMPY-01914) |
抗原种属 | Human |
研究领域 | ITIM/ITAM Immunoreceptors and Related Molecules |
储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
运输方式 | Shipping with blue ice. |
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