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Anti-SLAMF6 Antibody-FITC (4Z355)

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产品编号 TMAY-02159F
别名 SLAM family member 6, SF2000, NTB-A, NTBA, Ly108, KALIb, KALI, CD352

Anti-SLAMF6 Antibody-FITC (4Z355) 是一种 FITC-conjugated Rabbit 抗体,靶向 SLAMF6。Anti-SLAMF6 Antibody-FITC (4Z355) 可用于 FCM。

Anti-SLAMF6 Antibody-FITC (4Z355)

Anti-SLAMF6 Antibody-FITC (4Z355)

Rating icon 还可以
产品编号 TMAY-02159F 别名 SLAM family member 6, SF2000, NTB-A, NTBA, Ly108, KALIb, KALI, CD352

Anti-SLAMF6 Antibody-FITC (4Z355) 是一种 FITC-conjugated Rabbit 抗体,靶向 SLAMF6。Anti-SLAMF6 Antibody-FITC (4Z355) 可用于 FCM。

规格价格库存数量
25 T
¥ 685
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100 T
¥ 2,195
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产品介绍

生物活性
产品描述
Anti-SLAMF6 Antibody-FITC (4Z355) is a FITC-conjugated Rabbit antibody targeting SLAMF6. Anti-SLAMF6 Antibody-FITC (4Z355) can be used in FCM.
别名SLAM family member 6, SF2000, NTB-A, NTBA, Ly108, KALIb, KALI, CD352
Ig Type
Monoclonal Rabbit IgG
克隆号
4Z355
交叉反应
Human
验证活性
Flow cytometric analysis of Human SLAMF6(CD352) expression on human whole blood lymphocytes. Cells were stained with FITC-conjugated anti-Human SLAMF6(CD352). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes.
应用
FCM
推荐剂量
10 μl/Test, 0.1 mg/ml
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human Ly108/SLAMF6 (rh Ly108/SLAMF6; TMPY-01914; Q96DU3-1; Met1-Met226) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
纯化方式Protein A
性状Liquid
缓冲液PBS solution containing 0.5% BSA and 0.03%ProClin300
研究背景SLAM family member 6, also known as Activating NK receptor, NK-T-B-antigen, NTB-A, SLAMF6, KALI and Ly18, is a single-pass type I membrane protein that belongs to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6 / Ly18 contains one Ig-like (immunoglobulin-like) domain. It is expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes. SLAMF6 / Ly18 triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors. SLAMF6 / Ly18 is a homodimer. It interacts with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP. SLAMF6 / Ly18 undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. SLAMF6 / Ly18 can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients.
偶联与修饰
偶联
FITC
其他可选修饰符
Unconjugated/APC/PE
可提供抗体种类
4
抗原信息
免疫原
Recombinant Human Ly108/SLAMF6 Protein (TMPY-01914)
抗原种属
Human
研究领域
ITIM/ITAM Immunoreceptors and Related Molecules
存储&运输
储存方式Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
运输方式Shipping with blue ice.

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