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Anti-ITGAL Antibody (6D918)

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Anti-ITGAL Antibody (6D918)
产品编号 TMAH-00645
别名 CD11A

Anti-ITGAL Antibody (6D918) 是一种抗体,靶向 ITGAL。Anti-ITGAL Antibody (6D918) 可用于 ELISA, WB, IF Recommended dilution: WB:1:500-1:2000, IF:1:50-1:200。

Anti-ITGAL Antibody (6D918)

Anti-ITGAL Antibody (6D918)

Rating icon 还可以
Anti-ITGAL Antibody (6D918)
产品编号 TMAH-00645 别名 CD11A

Anti-ITGAL Antibody (6D918) 是一种抗体,靶向 ITGAL。Anti-ITGAL Antibody (6D918) 可用于 ELISA, WB, IF Recommended dilution: WB:1:500-1:2000, IF:1:50-1:200。

规格价格库存数量
50 μL
¥ 1,305
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100 μL
¥ 2,190
5日内发货
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产品介绍

生物活性
产品描述
Anti-ITGAL Antibody (6D918) is an antibody targeting ITGAL. Anti-ITGAL Antibody (6D918) can be used in ELISA, WB, IF Recommended dilution: WB:1:500-1:2000, IF:1:50-1:200.
别名CD11A
Ig Type
Rabbit IgG
克隆号
6D918
交叉反应
Human
验证活性
1. Western Blot
-Positive WB detected in: THP-1 whole cell lysate
-All lanes: ITGAL antibody at 1:2000
-Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution
-Predicted band size: 129, 135, 120 kDa
-Observed band size: 130 kDa
2. Immunofluorescence staining of THP-1 cell with TMAH-00645 at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 490-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
应用
推荐剂量
WB:1:500-1:2000; IF:1:50-1:200.
抗体种类
Monoclonal
亚细胞定位Cell membrane; Single-pass type I membrane protein.
构建方式Recombinant Antibody
纯化方式Affinity-chromatography
性状Liquid
缓冲液Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin ITGAL/ITGB2 is a receptor for F11R. Integin ITGAL/ITGB2 is a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL. Involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. Contributes to natural killer cell cytotoxicity. Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils. Required for generation of common lymphoid progenitor cells in bone marrow, indicating a role in lymphopoiesis. Integrin ITGAL/ITGB2 in association with ICAM3, contributes to apoptotic neutrophil phagocytosis by macrophages.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthetic peptide: Human ITGAL
抗原种属
Human
基因ID
Uniprot ID
研究领域
Immunology, Signal transduction, Stem cells
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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