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Anti-IGFBP-2 Antibody (1S652)
还可以产品编号 TMAY-03888
Anti-IGFBP-2 Antibody (1S652) 是一种 Mouse 抗体，靶向 IGFBP-2。Anti-IGFBP-2 Antibody (1S652) 可用于 IHC-P。
Anti-IGFBP-2 Antibody (1S652)
Anti-IGFBP-2 Antibody (1S652)
还可以产品编号 TMAY-03888
Anti-IGFBP-2 Antibody (1S652) 是一种 Mouse 抗体，靶向 IGFBP-2。Anti-IGFBP-2 Antibody (1S652) 可用于 IHC-P。
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产品介绍
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偶联与修饰
抗原信息
| 产品描述 | Anti-IGFBP-2 Antibody (1S652) is a Mouse antibody targeting IGFBP-2. Anti-IGFBP-2 Antibody (1S652) can be used in IHC-P. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 1S652 |
| 交叉反应 | Rhesus |
| 验证活性 | 1. Immunochemical staining of Rhesus IGFBP2 in Rhesus liver with mouse monoclonal antibody (1:30, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of Rhesus IGFBP2 in Rhesus kidney with mouse monoclonal antibody (1:30, formalin-fixed paraffin embedded sections). 3. Immunochemical staining of Rhesus IGFBP2 in Rhesus heart with mouse monoclonal antibody (1:30, formalin-fixed paraffin embedded sections). |
| 应用 | IHC-P |
| 推荐剂量 | IHC-P: 1:20-1:80 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Rhesus IGFBP-2 / IGFBP2 ( TMPY-02969; XP_001087071.1; Met1-Gln324). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | IGFBP-2, also known as IGFBP2, is an insulin-like growth factor-binding protein (IGFBP). IGFBPs prolong the half-life of the IGFs, control bioavailability, activity, and distribution of insulin-like growth factor (IGF) through high-affinity IGFBP/IGF complexes. Six high-affinity IGF-binding proteins (IGFBP-1 to -6) have been identified. The six IGFBPs are structurally related but encoded by distinct genes. IGFBPs have a high affinity for IGFs. Some members of the IGFBP family have been consistently shown to inhibit IGF actions by preventing them from gaining access to the IGF receptors, while others potentiate IGF actions by facilitating the ligand-receptor interaction. IGFBP-2 is overexpressed in many malignancies and is often correlated with an increasingly malignant status of the tumor, pointing to the potential involvement of IGFBP-2 in tumorigenesis. It contains 1 IGFBP N-terminal domain and 1 thyroglobulin type-1 domain. It inhibits IGF-mediated growth and developmental rates. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Rhesus IGFBP-2 / IGFBP2 Protein (TMPY-02969) |
| 抗原种属 | Rhesus |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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