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LASN01 是一种针对白介素-11 受体 alpha (IL-11Ra) 的首创人源化单克隆抗体,通过特异性识别并结合 IL-11R 来阻断其与 IL-11 配体的相互作用,从而在实验研究中作为抑制肌成纤维细胞分化、阻断 STAT3 信号传导级联反应及研究甲状腺相关眼病 (TED) 与特发性肺纤维化 (IPF) 病理机制的药理学工具。
LASN01 是一种针对白介素-11 受体 alpha (IL-11Ra) 的首创人源化单克隆抗体,通过特异性识别并结合 IL-11R 来阻断其与 IL-11 配体的相互作用,从而在实验研究中作为抑制肌成纤维细胞分化、阻断 STAT3 信号传导级联反应及研究甲状腺相关眼病 (TED) 与特发性肺纤维化 (IPF) 病理机制的药理学工具。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 1 mg | ¥ 12,000 | 待询 | |
| 5 mg | 待询 | 待询 |
| 产品描述 | LASN01 represents a highly specialized first-in-class humanized monoclonal antibody specifically engineered to target the human interleukin-11 receptor alpha subunit with exceptional binding affinity and selectivity, effectively facilitating the measurable blockade of IL-11-mediated signaling pathways across various preclinical experimental models to evaluate the inhibition of fibroinflammatory processes in specialized research environments. |
| 反应种属 | Human |
| 应用 | ELISA FACS Functional assay |
| 抗体种类 | Monoclonal |
| 缓冲液 | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| 内毒素 | <1.0 EU/mg |
| 同型 | IgG4SP-opti |
| 偶联 | Unconjugated |
| Uniprot ID | |
| 靶点 | IL-11RA |
| 存储 | store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature. |
对于不同动物的给药剂量换算,您也可以参考 更多