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Anti-Dystrophin Antibody (7T61)
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产品编号 TMAH-00357
别名 Dystrophin, DMD
Anti-Dystrophin Antibody (7T61) 是一种抗体，靶向 Dystrophin。Anti-Dystrophin Antibody (7T61) 可用于 ELISA, IHC。
Anti-Dystrophin Antibody (7T61)
Anti-Dystrophin Antibody (7T61)
还可以产品编号 TMAH-00357 别名 Dystrophin, DMD
Anti-Dystrophin Antibody (7T61) 是一种抗体，靶向 Dystrophin。Anti-Dystrophin Antibody (7T61) 可用于 ELISA, IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,305 | 5日内发货 | |
| 100 μL | ¥ 2,185 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Dystrophin Antibody (7T61) is an antibody targeting Dystrophin. Anti-Dystrophin Antibody (7T61) can be used in ELISA, IHC. |
| 别名 | Dystrophin, DMD |
| Ig Type | Rabbit IgG |
| 克隆号 | 7T61 |
| 交叉反应 | Human |
| 验证活性 | 1. IHC image of TMAH-00357 diluted at 1:100 and staining in paraffin-embedded human heart tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. 2. IHC image of TMAH-00357 diluted at 1:100 and staining in paraffin-embedded human skeletal muscle tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. |
| 应用 | |
| 推荐剂量 | IHC:1:50-1:200. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell junction, synapse, postsynaptic cell membrane. |
| 组织特异性 | Expressed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma. Expressed in brain, muscle, kidney, lung and testis. Most tissues contain transcripts of multiple isoforms. Isoform 15: Only isoform to be detected in heart and liver |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Anchors the extracellular matrix to the cytoskeleton via F-actin. Ligand for dystroglycan. Component of the dystrophin-associated glycoprotein complex which accumulates at the neuromuscular junction (NMJ) and at a variety of synapses in the peripheral and central nervous systems and has a structural function in stabilizing the sarcolemma. Also implicated in signaling events and synaptic transmission. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: Human Dystrophin |
| 抗原种属 | Human |
| 基因名称 | DMD |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | Neuroscience, Signal transduction, Stem cells |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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