Name: Anti-PACAP38 Antibody
Brand: TargetMol
SKU: T9901A-1283
Rating: 4.5 (1 reviews)

生物活性

产品描述	Anti-PACAP38 Antibody represents a highly specialized monoclonal antibody specifically engineered to target the human pituitary adenylate cyclase-activating polypeptide 38 isoform with exceptional binding affinity and selectivity, effectively facilitating the measurable neutralization of ligand-mediated signaling within the GPCR/G Protein pathway to evaluate its functional role in neurovascular regulation during strictly monitored laboratory observation periods and functional cyclic AMP accumulation assays to ensure high experimental sensitivity.
靶点活性	PACAP:2.3 pM (Kd)
体外活性	在基于细胞的报告基因实验中，Anti-PACAP38 Antibody (ALD1910) 以高亲和力强效地中和了由 PACAP38 诱导的 cAMP 产生 [1]。
体内活性	在大鼠血管扩张模型中，通过全身给药方式给予 Anti-PACAP38 Antibody (ALD1910) 显著抑制了由 PACAP38 诱导的脑膜血流增加 [1]。
别名	抗PACAP38抗体
反应种属	Human
应用	ELISA FACS Functional assay
抗体种类	Monoclonal
缓冲液	Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
内毒素	<1.0 EU/mg

抗体信息

同型

IgG1

偶联与修饰

偶联	Unconjugated

抗原信息

Uniprot ID	P18509
靶点	PACAP38

储存&溶解度

存储

Anti-PACAP38 Antibody