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Anti-AKIRIN1 Polyclonal Antibody

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货号 TMAB-02405

Anti-AKIRIN1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 AKIRIN1。Anti-AKIRIN1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-AKIRIN1 Polyclonal Antibody

Anti-AKIRIN1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-02405

Anti-AKIRIN1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 AKIRIN1。Anti-AKIRIN1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-AKIRIN1 Polyclonal Antibody is a Rabbit antibody targeting AKIRIN1. Anti-AKIRIN1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Dog,Horse,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nuclear
组织特异性Widely expressed with the highest expression in heart, liver, placenta and peripheral blood leukocytes.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景AKIRIN1 is dispensable in the mouse, and neither knockout mice nor cells derived from them have obvious distinctive phenotypes. In contrast, Akirin2 is required for development in the mouse and knockout of both Akirin homologs in mice show that Akirin2 is required downstream of toll-like receptor (TLR), TNF-alpha and IL-1beta signaling, and for the production of IL-6. Akirin2 is functionally closer to the single gene in Drosophila, as the homozygous null D. melanogaster Akirin mutants show a similar, mid-to-early embryonic death.The highly conserved, nuclear-localized AKIRIN1 and Akirin2 proteins critically regulate the transcription of NF-kB dependent genes and are required for defense against Gram-negative bacteria in the immune deficiency and NF-kB pathways.
抗原信息
免疫原
KLH conjugated synthetic peptide: human AKIRIN1
抗原种属
Human
基因名称
AKIRIN1
基因ID
蛋白名称
Akirin-1
Uniprot ID
化学信息
分子量Theoretical: 22 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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