生物活性

产品描述	HLA-A02:01&B2M&NPM1-CLAV (CLAVEEVSL) Monomer Protein, Human, MHC (His & Avi), Biotinylated is expressed in HEK293 Cells. The accession number is A0A140T913(HLA-A02:01)&P61769(B2M)&CLAVEEVSL.
生物活性	Activity has not been tested. It is theoretically active, but we cannot guarantee it.
研究背景	The nucleophosmin (NPM1) mutant protein, a leukemia-associated antigen characterized by its leukemia-restricted expression and immunogenic potential, has emerged as a promising therapeutic target for acute myeloid leukemia (AML) immunotherapy. Among its immunogenic epitopes, the CLAVEEVSL peptide derived from the full C-terminal region of the NPM1-mutated isoform demonstrates potent immunogenicity, making it a prime candidate for T cell-based immunotherapies.
种属	Human
表达系统	HEK293 Cells
标签	C-His-Avi
蛋白编号	A0A140T913(HLA-A*02:01)&P61769(B2M)&CLAVEEVSL
蛋白构建	Gly25-Thr305 (HLA-A*02:01), Ile21-Met119 (B2M) and CLAVEEVSL peptide
蛋白纯度	> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
缓冲液	Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
别名	NPM1-CLAV (CLAVEEVSL), NPM1-CLAV, CLAVEEVSL
内毒素	< 1 EU/μg of the protein as determined by the LAL method.

化学信息

分子量	50.4 kDa (Predicted); 52-60 kDa (Reducing condition, due to glycosylation)

储存&溶解度

运输方式

In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.

存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

实际储存温度请以COA为准

**HLA-A*02:01&B2M&NPM1-CLAV (CLAVEEVSL) Monomer Protein, Human, MHC (His & Avi), Biotinylated**

HLA-A*02:01&B2M&NPM1-CLAV (CLAVEEVSL) Monomer Protein, Human, MHC (His & Avi), Biotinylated

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