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顶部生物活性储存和溶解信息计算器

Anti-Phospho-AURKB (Thr232) Polyclonal Antibody

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Anti-Phospho-AURKB (Thr232) Polyclonal Antibody
产品编号 TMAC-00347
别名 p-AURKB (Thr232), p-AURKB (T232), AURKB (p-Thr232), AURKB (p-T232)

Anti-Phospho-AURKB (Thr232) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-AURKB (Thr232)。Anti-Phospho-AURKB (Thr232) Polyclonal Antibody 可用于 WB。

Anti-Phospho-AURKB (Thr232) Polyclonal Antibody

Anti-Phospho-AURKB (Thr232) Polyclonal Antibody

Rating icon 还可以
Anti-Phospho-AURKB (Thr232) Polyclonal Antibody
产品编号 TMAC-00347 别名 p-AURKB (Thr232), p-AURKB (T232), AURKB (p-Thr232), AURKB (p-T232)

Anti-Phospho-AURKB (Thr232) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-AURKB (Thr232)。Anti-Phospho-AURKB (Thr232) Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,480
5日内发货
100 μL
¥ 2,230
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-AURKB (Thr232) Polyclonal Antibody is a Rabbit antibody targeting Phospho-AURKB (Thr232). Anti-Phospho-AURKB (Thr232) Polyclonal Antibody can be used in WB.
别名p-AURKB (Thr232), p-AURKB (T232), AURKB (p-Thr232), AURKB (p-T232)
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of extracts from COS7 cells treated with Nocodazole using Phospho-AurB (Thr232) antibody TMAC-00347. The lane on the right is treated with the antigen-specific peptide.
应用
WB
推荐剂量
WB: 1:500-1000
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
性状Liquid
缓冲液Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. AURKB phosphorylates the CPC complex subunits BIRC5/survivin, CDCA8/borealin and INCENP. Phosphorylation of INCENP leads to increased AURKB activity.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
Peptide sequence around phosphorylation site of threonine 232 (R-K-T(p)-M-C) derived from Human AurB
抗原种属
human
Uniprot ID
Q96GD4
化学信息
分子量Actual: 39 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

pAURKB (Thr232)pAURKB (T232)AURKB (pThr232)AURKB (pT232)AURKB (phospho-Thr232)AURKB (phospho-T232)

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