购物车
- 全部删除
- 您的购物车当前为空
Anti-BCL-XL Antibody (2A140) 是一种抗体,靶向 BCL-XL。Anti-BCL-XL Antibody (2A140) 可用于 ELISA, WB, IHC。
Anti-BCL-XL Antibody (2A140) 是一种抗体,靶向 BCL-XL。Anti-BCL-XL Antibody (2A140) 可用于 ELISA, WB, IHC。
产品描述 | Anti-BCL-XL Antibody (2A140) is an antibody targeting BCL-XL. Anti-BCL-XL Antibody (2A140) can be used in ELISA, WB, IHC. |
别名 | PPP1R52, bcl-xS, BCLXS, BCL-XL/S, bcl-xL, BCLXL, Bcl-X, BCLX, BCL2-like 1, BCL2L |
Ig Type | Rabbit IgG |
克隆号 | 2A140 |
交叉反应 | Human, Mouse, Rat |
验证活性 | 1. Western Blot -Positive WB detected in: K562 whole cell lysate, Hela whole cell lysate, NIH/3T3 whole cell lysate, Rat Brain whole cell lysate, Mouse Brain whole cell lysate -All lanes: Bcl-XL antibody at 1:1000 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 27, 19, 26 kDa -Observed band size: 30 kDa 2. IHC image of TMAH-00111 diluted at 1:100 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. |
应用 | ELISA, WB, IHC |
推荐剂量 | WB:1:500-1:5000; IHC:1:50-1:200. |
抗体种类 | Monoclonal |
亚细胞定位 | [Isoform Bcl-X(L)]: Mitochondrion inner membrane. Mitochondrion outer membrane. Mitochondrion matrix. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus membrane; Single-pass membrane protein; Cytoplasmic side. |
构建方式 | Recombinant Antibody |
纯化方式 | Affinity-chromatography |
性状 | Liquid |
缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis.; Isoform Bcl-X(L) also regulates presynaptic plasticity, including neurotransmitter release and recovery, number of axonal mitochondria as well as size and number of synaptic vesicle clusters. During synaptic stimulation, increases ATP av... |
偶联 | Unconjugated |
免疫原 | A synthesized peptide derived from human Bcl-XL |
抗原种属 | Human |
基因ID | 598 |
Uniprot ID | |
研究领域 | Cancer, Cell biology, Metabolism, Signal transduction |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
评论内容