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ULBP-6 Protein, Human, Recombinant (hFc)

Synonyms: ULBP6, retinoic acid early transcript 1L, RAET1L
货号 TMPY-00190 一键复制产品信息
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ULBP6/RAET1L, is a polymorphic locus that expresses a functional transcript. ULBP6 had a more restricted expression profile in cell lines and primary human tissues than other NKG2D ligands, but expression was detected in several human papillomavirus-positive cervical carcinoma cell lines and was inducible on infection with human CMV. Expression of ULBP6 on target cells induced a significant increase in NK-cell killing. ULBP-6 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.5 kDa and the accession number is AAK91503.1.

ULBP-6 Protein, Human, Recombinant (hFc)

一键复制产品信息
Rating icon 还可以
SPR兼容缓冲液
货号 TMPY-00190

别名 ULBP6, retinoic acid early transcript 1L, RAET1L

ULBP6/RAET1L, is a polymorphic locus that expresses a functional transcript. ULBP6 had a more restricted expression profile in cell lines and primary human tissues than other NKG2D ligands, but expression was detected in several human papillomavirus-positive cervical carcinoma cell lines and was inducible on infection with human CMV. Expression of ULBP6 on target cells induced a significant increase in NK-cell killing. ULBP-6 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.5 kDa and the accession number is AAK91503.1.

ULBP-6 Protein, Human, Recombinant (hFc)
规格价格库存数量
5 μg
¥ 428
6-8日内发货
10 μg
¥ 683
6-8日内发货
20 μg
¥ 1,130
5日内发货
50 μg
¥ 2,270
5日内发货
100 μg
¥ 4,430
5日内发货
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产品介绍


生物活性
产品描述
ULBP6/RAET1L, is a polymorphic locus that expresses a functional transcript. ULBP6 had a more restricted expression profile in cell lines and primary human tissues than other NKG2D ligands, but expression was detected in several human papillomavirus-positive cervical carcinoma cell lines and was inducible on infection with human CMV. Expression of ULBP6 on target cells induced a significant increase in NK-cell killing. ULBP-6 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.5 kDa and the accession number is AAK91503.1.
生物活性
Measured by its binding ability in a functional ELISA. Immobilized human His-NKG2D(78-216) at 10 μg/ml (100 μl/well) can bind RAET1L-Fc, The EC50 of RAET1L-Fc is 13-30ng/ml.
研究背景
ULBP6/RAET1L, is a polymorphic locus that expresses a functional transcript. ULBP6 had a more restricted expression profile in cell lines and primary human tissues than other NKG2D ligands, but expression was detected in several human papillomavirus-positive cervical carcinoma cell lines and was inducible on infection with human CMV. Expression of ULBP6 on target cells induced a significant increase in NK-cell killing.
种属
Human
表达系统
HEK293 Cells
标签C-hFc
蛋白编号AAK91503.1
蛋白构建A DNA sequence encoding the human RAET1L (AAK91503.1) (Met1-Ser217) was expressed with the Fc region of human IgG1 at the C-terminus. Predicted N terminal: Arg 26
蛋白纯度
> 90 % as determined by SDS-PAGE.
蛋白性状Lyophilized powder
缓冲液Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
别名ULBP6, retinoic acid early transcript 1L, RAET1L
内毒素< 1.0 EU/μg of the protein as determined by the LAL method.
化学信息
分子量48.5 kDa (predicted)
储存&溶解度
运输方式In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
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