购物车
  • 全部删除
  • TargetMol
    您的购物车当前为空
顶部生物活性储存和溶解信息计算器

Anti-2B4/CD244 Antibody (1B831)

Rating icon 还可以
Anti-2B4/CD244 Antibody (1B831)
产品编号 TMAY-00155
别名 SLAMF4, Nmrk, NKR2B4, NAIL, CD244 molecule, natural killer cell receptor 2B4, 2B4

Anti-2B4/CD244 Antibody (1B831) 是一种 Rabbit 抗体，靶向 2B4/CD244。Anti-2B4/CD244 Antibody (1B831) 可用于 WB,ELISA(Cap),IP。

Anti-2B4/CD244 Antibody (1B831)
331

Anti-2B4/CD244 Antibody (1B831)

Rating icon 还可以
Anti-2B4/CD244 Antibody (1B831)
产品编号 TMAY-00155 别名 SLAMF4, Nmrk, NKR2B4, NAIL, CD244 molecule, natural killer cell receptor 2B4, 2B4

Anti-2B4/CD244 Antibody (1B831) 是一种 Rabbit 抗体，靶向 2B4/CD244。Anti-2B4/CD244 Antibody (1B831) 可用于 WB,ELISA(Cap),IP。

规格价格库存数量
20 μL
¥ 790
5日内发货
100 μL
¥ 2,289
5日内发货
大包装 & 定制
加入购物车
TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
查看更多
联系我们获取更多批次信息
资源下载
产品操作手册

产品介绍

生物活性
产品描述
Anti-2B4/CD244 Antibody (1B831) is a Rabbit antibody targeting 2B4/CD244. Anti-2B4/CD244 Antibody (1B831) can be used in WB,ELISA(Cap),IP.
别名SLAMF4, Nmrk, NKR2B4, NAIL, CD244 molecule, natural killer cell receptor 2B4, 2B4
Ig Type
Rabbit IgG
克隆号
1B831
交叉反应
Human
验证活性
1. Anti-2B4 rabbit monoclonal antibody at 1:500 dilution.
-Lane A: Daudi Whole Cell lysate.
-Lysates/proteins at 30 μg per lane.
-Secondary
-Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.
-Developed using the Odyssey technique.
-Performed under reducing conditions.
-Predicted band size:42 kDa.
-Observed band size:28 kDa(We are unsure as to the identity of these extra bands.)
2. 2B4 was immunoprecipitated using:
-Lane A:0.5 mg Daudi Whole Cell Lysate.
-2 µL anti-2B4 rabbit monoclonal antibody and 15 μl of 50 % Protein G agarose.
-Primary antibody:
-Anti-2B4 rabbit monoclonal antibody, at 1:200 dilution.
-Secondary antibody:
-Dylight 800-labeled antibody to rabbit IgG (H+L), at 1:5000 dilution.
-Developed using the odyssey technique.
-Performed under reducing conditions.
-Predicted band size: 42 kDa.
-Observed band size: 28 kDa
应用
WB,ELISA(Cap),IP
推荐剂量
WB: 1:500-1:2000; IP: 1-4 μL/mg of lysate; ELISA(Cap): 1:250-1:2000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human 2B4 / CD244 (rh 2B4 / CD244; TMPY-01568; NP_057466.1; Met1-Arg221).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景The CD244 antigen, also known as 2B4, is a cell surface glycoprotein implicated in the regulation of natural killer and T lymphocyte function. 2B4 is a member of the signaling lymphocyte activation molecule (SLAM)-related receptor family and is important for stimulating NK cell cytotoxicity and cytokine production, which is expressed on all NK cells, a subpopulation of T cells, monocytes and basophils. The 2B4 antigen identified on NK cells and T cells is capable of transmitting stimulatory signals and non-MHC-restricted killing. Reported as an activating receptor, human 2B4 can effectively activate and enhance NK cell–mediated cytotoxicity, induce secretion of IFN-γ and matrix metalloproteinases (MMPs), as well as NK cell invasiveness. As a cell surface glycoprotein of the Ig-superfamily structurally related to CD2-like molecules such as CD2, CD48, CD58, CD84, Ly-9, and SLAM, 2B4 (CD244) is expressed on all human NK cells, a subpopulation of T cells, basophils and monocytes. 2B4 activates NK cell mediated cytotoxicity, induces secretion of IFN-gamma and matrix metalloproteinases, and NK cell invasiveness.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: IP AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human 2B4 / CD244 protein (TMPY-01568)
抗原种属
Human
研究领域
Cancer Drug Targets, ITIM/ITAM Immunoreceptors and Related Molecules
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器

关键词

SLAMF-4SLAMF 4

评论列表

4个月前
5.0
Rating icon 很棒

评论内容

233
Related Tags: buy Anti-2B4/CD244 Antibody (1B831) | purchase Anti-2B4/CD244 Antibody (1B831) | Anti-2B4/CD244 Antibody (1B831) cost | order Anti-2B4/CD244 Antibody (1B831)