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MTHFS Protein, Human, Recombinant (His)

MTHFS Protein, Human, Recombinant (His)

产品编号 TMPJ-00989
别名: 5-formyltetrahydrofolate cyclo-ligase, 10-methenyl-tetrahydrofolate synthetase, MTHFS, 5, 10-methenyl-tetrahydrofolate synthetase, 5, Methenyl-THF synthetase

5-formyltetrahydrofolate cyclo-ligase (MTHFS) belongs to the 5-formyltetrahydrofolate cyclo-ligase family. It is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, contributes to tetrahydrofolate metabolism. MTHFS helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids. An increased activity of the encoded protein can result in an increased folate turnover rate and folate depletion.

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MTHFS Protein, Human, Recombinant (His)
规格 价格/CNY 货期 数量
10 μg ¥ 1,170 5日内发货
50 μg ¥ 3,470 5日内发货
500 μg ¥ 12,100 5日内发货
1 mg ¥ 18,900 5日内发货
药物设计专题培训
千万补贴 助力科研
BCA蛋白浓度测定试剂盒限时半价
产品目录号及名称: MTHFS Protein, Human, Recombinant (His) (TMPJ-00989)
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产品性质
产品描述 5-formyltetrahydrofolate cyclo-ligase (MTHFS) belongs to the 5-formyltetrahydrofolate cyclo-ligase family. It is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, contributes to tetrahydrofolate metabolism. MTHFS helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids. An increased activity of the encoded protein can result in an increased folate turnover rate and folate depletion.
种属 Human
表达系统 E. coli
标签 C-6xHis
蛋白编号 P49914
别名 5-formyltetrahydrofolate cyclo-ligase, 10-methenyl-tetrahydrofolate synthetase, MTHFS, 5, 10-methenyl-tetrahydrofolate synthetase, 5, Methenyl-THF synthetase
氨基酸序列 Met1-Ala203
蛋白构建 Met1-Ala203
蛋白纯度 Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量 28 KDa (reducing condition)
内毒素 < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 200 mM Nacl, 1 mM DTT, 50% Glycerol, pH 8.0.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 5-formyltetrahydrofolate cyclo-ligase (MTHFS) belongs to the 5-formyltetrahydrofolate cyclo-ligase family. It is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, contributes to tetrahydrofolate metabolism. MTHFS helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids. An increased activity of the encoded protein can result in an increased folate turnover rate and folate depletion.

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Keywords

MTHFS Protein, Human, Recombinant (His) 5-formyltetrahydrofolate cyclo-ligase 10-methenyl-tetrahydrofolate synthetase MTHFS 5, 10-methenyl-tetrahydrofolate synthetase 5 Methenyl-THF synthetase recombinant recombinant-proteins proteins protein

 

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