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Anti-HIF-2 alpha Polyclonal Antibody

Synonyms: PASD2, PAS domain-containing protein 2, MOP2, MOP 2, Member of pas superfamily 2, Member of PAS protein 2, Hypoxia inducible factor 2 alpha subunit, Hypoxia inducible factor 2 alpha, HLF, HIF2-alpha, HIF-2-alpha, HIF2A, HIF-1-alpha-like factor, EPAS1, EPAS 1, Endothelial PAS domain-containing protein 1, Endothelial PAS domain containing protein 1, ECYT4, Class E basic helix-loop-helix protein 73, bHLHe73, Basic helix loop helix PAS protein MOP2
货号 TMAB-00859 一键复制产品信息
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Anti-HIF-2 alpha Polyclonal Antibody 是一种 Rabbit 抗体，靶向 HIF-2 alpha。Anti-HIF-2 alpha Polyclonal Antibody 可用于 FCM, ICC/IF, WB。

Anti-HIF-2 alpha Polyclonal Antibody

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货号 TMAB-00859

别名 PASD2, PAS domain-containing protein 2, MOP2, MOP 2, Member of pas superfamily 2, Member of PAS protein 2, Hypoxia inducible factor 2 alpha subunit, Hypoxia inducible factor 2 alpha, HLF, HIF2-alpha, HIF-2-alpha, HIF2A, HIF-1-alpha-like factor, EPAS1, EPAS 1, Endothelial PAS domain-containing protein 1, Endothelial PAS domain containing protein 1, ECYT4, Class E basic helix-loop-helix protein 73, bHLHe73, Basic helix loop helix PAS protein MOP2

Anti-HIF-2 alpha Polyclonal Antibody 是一种 Rabbit 抗体，靶向 HIF-2 alpha。Anti-HIF-2 alpha Polyclonal Antibody 可用于 FCM, ICC/IF, WB。

Anti-HIF-2 alpha Polyclonal Antibody
规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-HIF-2 alpha Polyclonal Antibody is a Rabbit antibody targeting HIF-2 alpha. Anti-HIF-2 alpha Polyclonal Antibody can be used in FCM, ICC/IF, WB.
别名PASD2, PAS domain-containing protein 2, MOP2, MOP 2, Member of pas superfamily 2, Member of PAS protein 2, Hypoxia inducible factor 2 alpha subunit, Hypoxia inducible factor 2 alpha, HLF, HIF2-alpha, HIF-2-alpha, HIF2A, HIF-1-alpha-like factor, EPAS1, EPAS 1, Endothelial PAS domain-containing protein 1, Endothelial PAS domain containing protein 1, ECYT4, Class E basic helix-loop-helix protein 73, bHLHe73, Basic helix loop helix PAS protein MOP2
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human)
验证活性
25 μg total protein per Lane of various lysates probed with HIF 2 alpha polyclonal antibody, unconjugated (TMAB-00859) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at RT for 60 min.
verifiedActivity
应用FCMICC/IFWB
推荐剂量
FCM=1 μg/Test; ICC/IF=1:50-200; WB=1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus (Potential).
组织特异性Expressed in most tissues, with highest levels in lung, followed by heart, kidney, brain and liver. Predominantly expressed in endothelial cells. Also found in smooth muscle cells of the uterus, neurons, and brown adipose tissue. High expression in embryo
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景Transcription factor involved in the induction of oxygen regulated genes. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase expression. Activation requires recruitment of transcriptional coactivators such as CREBPB and probably EP300. Interaction with redox regulatory protein APEX seems to activate CTAD.
抗原信息
免疫原
KLH conjugated synthetic peptide: mouse HIF 2 Alpha
抗原种属
Mouse
基因名称
EPAS1
基因ID
13819
蛋白名称
Endothelial PAS domain-containing protein 1
Uniprot ID
P97481
研究领域
Response to hypoxia,HIF,HIF,HIF,HLH,Mitochondrial transcription,Hypoxia
功能
Transcription factor involved in the induction of oxygen regulated genes. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase expression. Activation requires recruitment of transcriptional coactivators such as CREBPB and probably EP300. Interaction with redox regulatory protein APEX seems to activate CTAD.
化学信息
分子量Theoretical: 96 kDa. Actual: 110 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器
  • 配液 计算器
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