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Anti-HIF-2 alpha Polyclonal Antibody
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产品编号 TMAB-00859
Anti-HIF-2 alpha Polyclonal Antibody 是一种 Rabbit 抗体，靶向 HIF-2 alpha。Anti-HIF-2 alpha Polyclonal Antibody 可用于 WB,ICC/IF,FCM。
Anti-HIF-2 alpha Polyclonal Antibody
Anti-HIF-2 alpha Polyclonal Antibody
还可以产品编号 TMAB-00859
Anti-HIF-2 alpha Polyclonal Antibody 是一种 Rabbit 抗体，靶向 HIF-2 alpha。Anti-HIF-2 alpha Polyclonal Antibody 可用于 WB,ICC/IF,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
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产品介绍
生物活性
抗原信息
| 产品描述 | Anti-HIF-2 alpha Polyclonal Antibody is a Rabbit antibody targeting HIF-2 alpha. Anti-HIF-2 alpha Polyclonal Antibody can be used in WB,ICC/IF,FCM. |
| Ig Type | IgG |
| 交叉反应 | Mouse,Rat (predicted:Human) |
| 验证活性 | 25 μg total protein per Lane of various lysates probed with HIF 2 alpha polyclonal antibody, unconjugated (TMAB-00859) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at RT for 60 min. |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000; ICC/IF: 1:50-200; FCM: 1:20-100 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nucleus (Potential). |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究背景 | Transcription factor involved in the induction of oxygen regulated genes. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase expression. Activation requires recruitment of transcriptional coactivators such as CREBPB and probably EP300. Interaction with redox regulatory protein APEX seems to activate CTAD. |
| 免疫原 | KLH conjugated synthetic peptide: mouse HIF 2 Alpha |
| 抗原种属 | Mouse |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | Response to hypoxia,HIF,HIF,HIF,HLH,Mitochondrial transcription,Hypoxia |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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