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Anti-Desmin Antibody (8B607) (ready to use)

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货号 TMAB-05096

Anti-Desmin Antibody (8B607) 是一种 Mouse 抗体,靶向 Desmin。Anti-Desmin Antibody (8B607) 可用于 IHC-P,IHC-Fr,ICC/IF,IF。

Anti-Desmin Antibody (8B607) (ready to use)

Anti-Desmin Antibody (8B607) (ready to use)

一键复制产品信息
Rating icon 还可以
货号 TMAB-05096

Anti-Desmin Antibody (8B607) 是一种 Mouse 抗体,靶向 Desmin。Anti-Desmin Antibody (8B607) 可用于 IHC-P,IHC-Fr,ICC/IF,IF。

规格价格库存数量
3 mL
¥ 550
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6 mL
¥ 965
5日内发货
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产品介绍


生物活性
产品描述
Anti-Desmin Antibody (8B607) is a Mouse antibody targeting Desmin. Anti-Desmin Antibody (8B607) can be used in IHC-P,IHC-Fr,ICC/IF,IF.
Ig Type
IgG1
克隆号
8B607
反应种属
Human
应用IHC-PIHC-FrICC/IFIF
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Cytoplasm.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M PBS (pH7.4) with 1% BSA and 0.02% Proclin300.
研究背景Desmin is a muscle-specific, type III intermediate filament that integrates the sarcolemma, Z disk, and nuclear membrane in sarcomeres and regulates sarcomere architecture. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z line structures. Defects in Desmin are the cause of desmin related cardio skeletal myopathy (CSM) also known as desmin related myopathy (DRM). CSM is characterized by skeletal muscle weakness associated with cardiac conduction blocks, arrhythmias, restrictive heart failure, and by intracytoplasmic accumulation of desmin reactive deposits in cardiac and skeletal muscle cells. A desmin related myopathy can have a distal onset, it is then known as hereditary distal myopathy (HDM). Defects in Desmin are also the cause of dilated cardiomyopathy type 1I (CMD1I). CMD1I is an autosomal form of dilated cardiomyopathy characterized by ventricular dilatation and impaired systolic function. Antidesmin antibodies are useful in identification of tumours of myogenic origin
抗原信息
免疫原
KLH conjugated synthetic peptide: human Desmin
抗原种属
Human
基因名称
DES
基因ID
蛋白名称
Desmin
Uniprot ID
功能
Desmin are class-III intermediate filaments found in muscle cells. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures.
化学信息
分子量Theoretical: 52 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 12 months, do not freeze.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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