规格

价格

库存

数量

10 mg

待询

25 mg

待询

50 mg

待询

生物活性

产品描述	Chlorin e6 trisodium (Ce6 trisodium) is a water-soluble derivative of chlorophyll and belongs to the chlorin photosensitizers with an absorption wavelength range of 600–670 nm. Upon photoexcitation, Chlorin e6 trisodium can produce characteristic red fluorescence for real-time observation of tumor boundaries and disease progression. Chlorin e6 trisodium can be used in photodynamic therapy (PDT)-related research and fluorescence diagnosis research of malignant tumors such as bladder cancer and related neoplastic lesions.
靶点活性	HeLa cells:13 μM, HeLa cells:0.83 μM
体外活性	方法：HeLa 细胞经 Chlorin e6 trisodium 处理并孵育 24 小时后进行照射。结果：Chlorin e6 trisodium 在 HeLa 细胞中表现出暗毒性，IC₅₀ 为 13 μM，同时表现出光毒性，IC₅₀ 为 0.83 μM [3]。
体内活性	方法：携带 MGH 异种移植瘤的 Balb/c 裸鼠经 Chlorin e6 trisodium（2.5‑5 mg/kg，静脉注射，单次剂量）处理并联合激光照射。结果：Chlorin e6 trisodium 表现出高光毒性，可诱导肿瘤组织产生显著更高的肿瘤坏死 [1][2]。
别名	二氢卟吩 e6 三钠盐, Ce6 trisodium

化学信息

分子量	662.62
分子式	C₃₄H₃₃N₄Na₃O₆
CAS No.	72984-36-2
Smiles	[O-]C(CC1=C2[C@H]([C@@H](C(C=C3NC(C(C=C)=C3C)=CC4=NC(C(CC)=C4C)=CC5=C(C)C(C([O-])=O)=C1N5)=N2)C)CCC([O-])=O)=O.[Na+].[Na+].[Na+]

储存&溶解度

存储

Keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

实际储存温度请以COA为准

溶解度信息

DMSO: 4.00 mg/mL (6.04 mM), Sonication is recommended.

H2O: 4.00 mg/mL (6.04 mM), Sonication is recommended.

溶液配制表

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	1.5092 mL	7.5458 mL	15.0916 mL	75.4580 mL
5 mM	0.3018 mL	1.5092 mL	3.0183 mL	15.0916 mL

该溶液配制表仅适用于固体产品。对于液体产品，请根据标明的浓度或密度计算稀释方案。

Chlorin e6 trisodium