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Anti-IL-4R Antibody-PE (6U88)
还可以产品编号 TMAY-00775P
Anti-IL-4R Antibody-PE (6U88) 是一种 PE-conjugated Rabbit 抗体，靶向 IL-4R。Anti-IL-4R Antibody-PE (6U88) 可用于 FCM。
Anti-IL-4R Antibody-PE (6U88)
Anti-IL-4R Antibody-PE (6U88)
还可以产品编号 TMAY-00775P
Anti-IL-4R Antibody-PE (6U88) 是一种 PE-conjugated Rabbit 抗体，靶向 IL-4R。Anti-IL-4R Antibody-PE (6U88) 可用于 FCM。
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抗原信息
| 产品描述 | Anti-IL-4R Antibody-PE (6U88) is a PE-conjugated Rabbit antibody targeting IL-4R. Anti-IL-4R Antibody-PE (6U88) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 6U88 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of human IL4R(CD124) expression on human whole blood lymphocytes. Cells were stained with PE-conjugated anti-Human IL4R(CD124) and APC-conjugated anti-Human CD19(BD Pharmingen™). The fluorescence histogram were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
| 应用 | FCM |
| 推荐剂量 | 5 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human IL-4R / CD124 (rh IL-4R / CD124; TMPY-01055; NP_000409.1; Met1-His232) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| 研究背景 | The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alters the behavior of the cell. Some CD proteins do not take part in the cell signal process but have other functions such as cell adhesion. CD124, also known as the interleukin 4 receptor (IL4R), is a typeⅠ transmembrane protein that can regulate IgE antibody production in B cells through binding to interleukin 4 and interleukin 13 and promote differentiation of Th2 cells through binding to interleukin 4. The membrane-bound form of CD124 can be hydrolyzed to a soluble form which can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. |
| 偶联 | PE |
| 其他可选修饰符 | Unconjugated/APC |
| 可提供抗体种类 | 3 |
| 免疫原 | Recombinant Human IL-4R/CD124 Protein (TMPY-01055) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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