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Anti-OSMR Antibody (5Q467)

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Anti-OSMR Antibody (5Q467)
产品编号 TMAY-01775
别名 OSMRB, oncostatin M receptor

Anti-OSMR Antibody (5Q467) 是一种 Rabbit 抗体,靶向 OSMR。Anti-OSMR Antibody (5Q467) 可用于 ELISA(Cap),FCM。

Anti-OSMR Antibody (5Q467)

Anti-OSMR Antibody (5Q467)

Rating icon 还可以
Anti-OSMR Antibody (5Q467)
产品编号 TMAY-01775 别名 OSMRB, oncostatin M receptor

Anti-OSMR Antibody (5Q467) 是一种 Rabbit 抗体,靶向 OSMR。Anti-OSMR Antibody (5Q467) 可用于 ELISA(Cap),FCM。

规格价格库存数量
20 μL
¥ 780
5日内发货
100 μL
¥ 2,279
5日内发货
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TargetMol 的所有产品仅用作科学研究或药证申报,不能被用于人体,我们不向个人提供产品和服务。请您遵守承诺用途,不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
抑制剂能否用于细胞实验?
可以的,我们的抑制剂都可以用于细胞/体外实验。但有些化合物还没有用于细胞实验的文献,这种情况下,建议您先做预实验,确保研究的可行性。
如何选择合适的溶剂?
常用的溶剂包括DMSO、水、乙醇等。建议您根据抑制剂给出的溶解度参考,选择合适的溶剂。如果该抑制剂可以溶于DMSO,建议使用没有吸潮新开封的 DMSO,如果有潮气污染,很容易带来抑制剂降解或难溶的问题。如果该抑制剂可以溶于水,建议您根据实验类型选择无菌水、生理盐水、无菌 PBS 、培养基等作为溶剂。
产品溶解需要超声吗?如果没有超声仪怎么办?
超声可以加快粉末的溶解速度,如果您的化合物溶解不了,建议您尝试超声。如果您没有超声仪,建议您选择较低母液浓度,或者较少粉末量,尝试溶解。
超声应使用什么仪器?
建议使用“超声清洗仪”,不推荐用“超声破碎仪”。
抑制剂加 DMSO 配成母液之后,能否放在常温的环境保存1周?
不建议这么做,母液配置好分装保存,建议存于 -20℃ 或 -80℃,尽量避免反复冻融。如果您订购的规格很大,可以考虑分装粉末保存,固体粉末是比较稳定的,-20℃ 可以保存三年。
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产品介绍

生物活性
产品描述
Anti-OSMR Antibody (5Q467) is a Rabbit antibody targeting OSMR. Anti-OSMR Antibody (5Q467) can be used in ELISA(Cap),FCM.
别名OSMRB, oncostatin M receptor
Ig Type
Rabbit IgG
克隆号
5Q467
交叉反应
Human
验证活性
Flow cytometric analysis of Human OSMR expression on HeLa cells. Cells were stained with purified anti-Human OSMR, then a FITC-conjugated second step antibody. The histogram were derived from gated events with the forward and side light-scatter characteristics of intact cells.
应用
ELISA(Cap),FCM
推荐剂量
FCM: 1:25-1:100; ELISA(Cap): 1:250-1:2000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human OSMR / IL-31RB (rh OSMR / IL-31RB; TMPY-01305; NP_003990.1; Met1-Met740).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Oncostatin-M specific receptor subunit beta also known as the oncostatin M receptor (OSMR) and Interleukin-31 receptor subunit beta (IL-31RB), is one of the receptor proteins for oncostatin M. OSMR is a member of the type I cytokine receptor family. IL-31RB/OSMR heterodimerizes with interleukin 6 signal transducer to form the type II oncostatin M receptor and with interleukin 31 receptor A to form the interleukin 31 receptor, and thus transduces oncostatin M and interleukin 31 induced signaling events. Mutations in IL-31RB/OSMR have been associated with familial primary localized cutaneous amyloidosis. Defects in IL-31RB/OSMR are the cause of amyloidosis primary localized cutaneous type 1 (PLCA1), also known as familial lichen amyloidosis of familial cutaneous lichen amyloidosis. PLCA1 is hereditary primary amyloidosis characterized by localized cutaneous amyloid deposition. This condition usually presents with itching (especially on the lower legs) and visible changes of skin hyperpigmentation and thickening (lichenification) that may be exacerbated by chronic scratching and rubbing. The amyloid deposits probably reflect a combination of degenerate keratin filaments, serum amyloid P component, and deposition of immunoglobulins.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
APC/PE
可提供抗体种类
3
抗原信息
免疫原
Recombinant Protein: Human OSMR / IL-31RB protein (TMPY-01305)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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