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Anti-LAMP3/CD208 Antibody (2U128)

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Anti-LAMP3/CD208 Antibody (2U128)
产品编号 TMAY-00948
别名 lysosomal associated membrane protein 3, LAMP3

Anti-LAMP3/CD208 Antibody (2U128) 是一种 Rabbit 抗体,靶向 LAMP3/CD208。Anti-LAMP3/CD208 Antibody (2U128) 可用于 ELISA(Cap)。

Anti-LAMP3/CD208 Antibody (2U128)
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Anti-LAMP3/CD208 Antibody (2U128)

Rating icon 还可以
Anti-LAMP3/CD208 Antibody (2U128)
产品编号 TMAY-00948 别名 lysosomal associated membrane protein 3, LAMP3

Anti-LAMP3/CD208 Antibody (2U128) 是一种 Rabbit 抗体,靶向 LAMP3/CD208。Anti-LAMP3/CD208 Antibody (2U128) 可用于 ELISA(Cap)。

规格价格库存数量
20 μL
¥ 785
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100 μL
¥ 2,289
5日内发货
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产品介绍

生物活性
产品描述
Anti-LAMP3/CD208 Antibody (2U128) is a Rabbit antibody targeting LAMP3/CD208. Anti-LAMP3/CD208 Antibody (2U128) can be used in ELISA(Cap).
别名lysosomal associated membrane protein 3, LAMP3
Ig Type
Rabbit IgG
克隆号
2U128
交叉反应
Human
应用
ELISA(Cap)
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human CD208 / DC-LAMP (rh CD208 / DC-LAMP; TMPY-01013; NP_055213.2; Lys28-Thr381).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Dendritic cell-lysosomal associated membrane protein (DC-LAMP)/CD208, also known as LAMP3, is a member of the lysosomal associated membrane protein (LAMP) family, which is specifically expressed by human dendritic cells (DCs) upon activation and therefore serves as a marker of human DC maturation. Confocal and immunoelectron microscopy showed that mouse DC-LAMP protein co-localizes with lbm180, a specific marker for the limiting membrane of lamellar bodies that contain surfactant protein B. The present study demonstrates that DC-LAMP is constitutively expressed by mouse, sheep, and human type II pneumocytes. DC-LAMP is constitutively expressed in normal type II pneumocytes. DC-LAMP is detected first in the activated human DC within MHC class II molecules-containing compartments just before the translocation of MHC class II-peptide complexes to the cell surface, suggesting a possible involvement in this process. Furthermore, overexpression of LAMP3 is actively involved in tumor invasion through increased migration into lymph-vascular spaces.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human CD208 / DC-LAMP Protein (TMPY-01013)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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