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Anti-LAMP3/CD208 Antibody (2U128) 是一种 Rabbit 抗体,靶向 LAMP3/CD208。Anti-LAMP3/CD208 Antibody (2U128) 可用于 ELISA(Cap)。
Anti-LAMP3/CD208 Antibody (2U128) 是一种 Rabbit 抗体,靶向 LAMP3/CD208。Anti-LAMP3/CD208 Antibody (2U128) 可用于 ELISA(Cap)。
产品描述 | Anti-LAMP3/CD208 Antibody (2U128) is a Rabbit antibody targeting LAMP3/CD208. Anti-LAMP3/CD208 Antibody (2U128) can be used in ELISA(Cap). |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 2U128 |
交叉反应 | Human |
应用 | ELISA(Cap) |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD208 / DC-LAMP (rh CD208 / DC-LAMP; TMPY-01013; NP_055213.2; Lys28-Thr381). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Dendritic cell-lysosomal associated membrane protein (DC-LAMP)/CD208, also known as LAMP3, is a member of the lysosomal associated membrane protein (LAMP) family, which is specifically expressed by human dendritic cells (DCs) upon activation and therefore serves as a marker of human DC maturation. Confocal and immunoelectron microscopy showed that mouse DC-LAMP protein co-localizes with lbm180, a specific marker for the limiting membrane of lamellar bodies that contain surfactant protein B. The present study demonstrates that DC-LAMP is constitutively expressed by mouse, sheep, and human type II pneumocytes. DC-LAMP is constitutively expressed in normal type II pneumocytes. DC-LAMP is detected first in the activated human DC within MHC class II molecules-containing compartments just before the translocation of MHC class II-peptide complexes to the cell surface, suggesting a possible involvement in this process. Furthermore, overexpression of LAMP3 is actively involved in tumor invasion through increased migration into lymph-vascular spaces. |
偶联 | Unconjugated |
免疫原 | Recombinant Human CD208 / DC-LAMP Protein (TMPY-01013) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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