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Anti-CD47 Antibody (1F304)

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产品编号 TMAH-00206
别名 OA3, MER6, IAP, CD47 molecule

Anti-CD47 Antibody (1F304) 是一种抗体,靶向 CD47。Anti-CD47 Antibody (1F304) 可用于 ELISA, FC。

Anti-CD47 Antibody (1F304)

Anti-CD47 Antibody (1F304)

Rating icon 还可以
产品编号 TMAH-00206 别名 OA3, MER6, IAP, CD47 molecule

Anti-CD47 Antibody (1F304) 是一种抗体,靶向 CD47。Anti-CD47 Antibody (1F304) 可用于 ELISA, FC。

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产品介绍

生物活性
产品描述
Anti-CD47 Antibody (1F304) is an antibody targeting CD47. Anti-CD47 Antibody (1F304) can be used in ELISA, FC.
别名OA3, MER6, IAP, CD47 molecule
Ig Type
hIgG1
克隆号
1F304
交叉反应
Human
验证活性
1. The Binding Activity of Human CD47 with Anti-CD47 recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CD47 at 2 μg/mL can bind Anti-CD47 recombinant antibody. The EC50 is 1.343-1.561 ng/mL.
2. Untransfected CT26 cells (green line) and transfected Human DLL3 & CD47 CT26 stable cells (red line) were stained with anti-CD47 antibody (TMAH-00206) (2µg/1*10^6 cells), washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.
3. Untransfected CT26 cells (green line) and transfected Human DLL3 & CD47 CT26 stable cells (red line) were stained with anti-DLL3 antibody (2µg/1*10^6 cells), washed and then followed by APC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.
应用
ELISA, FC
推荐剂量
FC:1:50-1:200.
抗体种类
Monoclonal
亚细胞定位Cell membrane; Multi-pass membrane protein.
构建方式Recombinant Antibody
纯化方式Affinity-chromatography
性状Liquid
缓冲液Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4.
研究背景Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus. Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transd...
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human CD47 protein
抗原种属
Human
基因ID
961
Uniprot ID
研究领域
Cancer, Immunology
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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