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Acetylcysteine-15N是一种 15N 标记的 Acetylcysteine (T0875)。Acetylcysteine (N-Acetylcysteine)是一种粘液溶解剂 (mucolytic agent),用于降低粘液的粘稠度,并作为 ROS 抑制剂发挥作用。它是半胱氨酸的前体,可通过中和花生四烯酸依赖的 5-脂氧合酶活性产生的毒性脂质来防止血红素诱导的铁中毒 (ferroptosis)。同时,Acetylcysteine 能诱导细胞凋亡 (apoptosis)并表现出抗流感病毒活性。此外,Acetylcysteine是药物输送中最稳定的半胱氨酸形式,适用于双硫死亡 (disulfidptosis)的研究。
Acetylcysteine-15N是一种 15N 标记的 Acetylcysteine (T0875)。Acetylcysteine (N-Acetylcysteine)是一种粘液溶解剂 (mucolytic agent),用于降低粘液的粘稠度,并作为 ROS 抑制剂发挥作用。它是半胱氨酸的前体,可通过中和花生四烯酸依赖的 5-脂氧合酶活性产生的毒性脂质来防止血红素诱导的铁中毒 (ferroptosis)。同时,Acetylcysteine 能诱导细胞凋亡 (apoptosis)并表现出抗流感病毒活性。此外,Acetylcysteine是药物输送中最稳定的半胱氨酸形式,适用于双硫死亡 (disulfidptosis)的研究。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 10 mg | 待询 | 待询 | |
| 50 mg | 待询 | 待询 |
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| 产品描述 | Acetylcysteine-15N is a version of Acetylcysteine (T0875) labeled with nitrogen-15 (\[^15N\]). Acetylcysteine (N-Acetylcysteine) functions as a mucolytic agent, effectively reducing mucus viscosity. As a reactive oxygen species (ROS) inhibitor, it serves as a cysteine precursor and prevents heme-induced ferroptosis by neutralizing toxic lipids produced via arachidonic acid-dependent 5-lipoxygenase activity. Additionally, Acetylcysteine (T0875) can induce apoptosis and exhibits antiviral activity against influenza. It represents the most stable form of cysteine for drug delivery and is utilized in studies of disulfidptosis. |
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. 实际储存温度请以COA为准 |
对于不同动物的给药剂量换算,您也可以参考 更多