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Anti-EphB6 Antibody (9W535)

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Anti-EphB6 Antibody (9W535)
产品编号 TMAY-00438
别名 EPH receptor B6

Anti-EphB6 Antibody (9W535) 是一种 Rabbit 抗体，靶向 EphB6。Anti-EphB6 Antibody (9W535) 可用于 ELISA。

Anti-EphB6 Antibody (9W535)
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Anti-EphB6 Antibody (9W535)

Rating icon 还可以
Anti-EphB6 Antibody (9W535)
产品编号 TMAY-00438 别名 EPH receptor B6

Anti-EphB6 Antibody (9W535) 是一种 Rabbit 抗体，靶向 EphB6。Anti-EphB6 Antibody (9W535) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 2,279
5日内发货
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产品介绍

生物活性
产品描述
Anti-EphB6 Antibody (9W535) is a Rabbit antibody targeting EphB6. Anti-EphB6 Antibody (9W535) can be used in ELISA.
别名EPH receptor B6
Ig Type
Rabbit IgG
克隆号
9W535
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human EphB6 (rh EphB6; TMPY-01424; NP_004436.1; Met 1-Ser 579).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Ephrins are divided into the ephrin-A (EFNA) class and the ephrin-B (EFNB) class based on their structures and sequence relationships. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. EphB6 is an unusual Eph receptor, lacking catalytic capacity due to alterations in its kinase domain. Interestingly, increased metastatic activity is associated with reduced EphB6 receptor expression in several tumor types, including breast cancer. This emphasizes the potential of EphB6 to act as a suppressor of cancer aggressiveness. EphB6 suppress cancer invasiveness through c-Cbl-dependent signaling, morphologic changes, and cell attachment and indicate that EphB6 may represent a useful prognostic marker and a promising target for therapeutic approaches. EphB6 can both positively and negatively regulate cell adhesion and migration, and suggest that tyrosine phosphorylation of the receptor by an Src family kinase acts as the molecular switch for the functional transition. In addition, Ephrin-B2 may be a physiological ligand for the EphB6 receptor.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human EphB6 protein (TMPY-01424)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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