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Anti-Alpha Synuclein Antibody (1L867) 是一种 Rabbit 抗体,靶向 Alpha Synuclein。Anti-Alpha Synuclein Antibody (1L867) 可用于 FCM, ICC/IF, IF, IHC-Fr, IHC-P, WB。
Anti-Alpha Synuclein Antibody (1L867) 是一种 Rabbit 抗体,靶向 Alpha Synuclein。Anti-Alpha Synuclein Antibody (1L867) 可用于 FCM, ICC/IF, IF, IHC-Fr, IHC-P, WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 795 | 5日内发货 | |
| 50 μL | ¥ 1,385 | 5日内发货 | |
| 100 μL | ¥ 2,495 | 5日内发货 |
| 产品描述 | Anti-Alpha Synuclein Antibody (1L867) is a Rabbit antibody targeting Alpha Synuclein. Anti-Alpha Synuclein Antibody (1L867) can be used in FCM, ICC/IF, IF, IHC-Fr, IHC-P, WB. |
| Ig Type | IgG |
| 克隆号 | 1L867 |
| 反应种属 | Human,Rat |
| 应用 | FCMICC/IFIFIHC-FrIHC-PWB |
| 推荐剂量 | FCM=1:50-100; ICC/IF=1:50-200; IF=1:200-800; IHC-Fr=1:200-800; IHC-P=1:200-800; WB=1:1000-2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm. Membrane. Nucleus. Cell junction, synapse. Note=Membrane-bound in dopaminergic neurons. |
| 组织特异性 | Expressed principally in brain but is also expressed in low concentrations in all tissues examined except in liver. Concentrated in presynaptic nerve terminals. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016]. |
| 免疫原 | A synthesized peptide: human alpha Synuclein |
| 抗原种属 | Human |
| 基因名称 | SNCA |
| 基因ID | |
| 蛋白名称 | alpha-synuclein |
| Uniprot ID | |
| 功能 | May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation. |
| 分子量 | Theoretical: 14 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |