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Anti-Coagulation Factor VIII/FVIII/F8 (Light Chain) Antibody (3O457) 是一种 Rabbit 抗体,靶向 Coagulation Factor VIII/FVIII/F8 (Light Chain)。Anti-Coagulation Factor VIII/FVIII/F8 (Light Chain) Antibody (3O457) 可用于 ELISA。
Anti-Coagulation Factor VIII/FVIII/F8 (Light Chain) Antibody (3O457) 是一种 Rabbit 抗体,靶向 Coagulation Factor VIII/FVIII/F8 (Light Chain)。Anti-Coagulation Factor VIII/FVIII/F8 (Light Chain) Antibody (3O457) 可用于 ELISA。
产品描述 | Anti-Coagulation Factor VIII/FVIII/F8 (Light Chain) Antibody (3O457) is a Rabbit antibody targeting Coagulation Factor VIII/FVIII/F8 (Light Chain). Anti-Coagulation Factor VIII/FVIII/F8 (Light Chain) Antibody (3O457) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 3O457 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human Coagulation Factor VIII / FVIII / F8 protein. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Coagulation Factor VIII, also known as FVIII and F8, is a member of the multicopper oxidase family. Coagulation Factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. It contains 3 F5/8 type A domains, 2 F5/8 type C domains and 6 plastocyanin-like domains. FVIII is synthesized in the liver, and perhaps in other tissues. It is a coagulation cofactor which circulates bound to von Willebrand factor and is part of the intrinsic coagulation pathway. It is a macromolecular complex composed of two separate entities, one of which, when deficient, results in hemophilia A, and the other, when deficient, results in von Willebrand's disease. Hemophilia A is a disorder of blood coagulation characterized by a permanent tendency to hemorrhage. About 5% of patients have severe hemophilia resulting in frequent spontaneous bleeding into joints, muscles and internal organs. Less severe forms are characterized by bleeding after trauma or surgery. |
偶联 | Unconjugated |
其他可选修饰符 | Biotin/HRP |
可提供抗体种类 | 3 |
免疫原 | Recombinant Human Coagulation Factor VIII / FVIII / F8 protein |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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