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Anti-SMAD4 Antibody (7P892)
还可以产品编号 TMAH-01109
别名 SMAD4, SMAD Family Member 4, SMAD 4, Mothers Against DPP Homolog 4, Mothers Against Decapentaplegic Homolog 4, MADH4, MAD Homolog 4, hSMAD4, DPC4, Deletion Target in Pancreatic Carcinoma 4
Anti-SMAD4 Antibody (7P892) 是一种抗体，靶向 SMAD4。Anti-SMAD4 Antibody (7P892) 可用于 ELISA, WB。
Anti-SMAD4 Antibody (7P892)
Anti-SMAD4 Antibody (7P892)
还可以产品编号 TMAH-01109 别名 SMAD4, SMAD Family Member 4, SMAD 4, Mothers Against DPP Homolog 4, Mothers Against Decapentaplegic Homolog 4, MADH4, MAD Homolog 4, hSMAD4, DPC4, Deletion Target in Pancreatic Carcinoma 4
Anti-SMAD4 Antibody (7P892) 是一种抗体，靶向 SMAD4。Anti-SMAD4 Antibody (7P892) 可用于 ELISA, WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,310 | 5日内发货 | |
| 100 μL | ¥ 2,190 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-SMAD4 Antibody (7P892) is an antibody targeting SMAD4. Anti-SMAD4 Antibody (7P892) can be used in ELISA, WB. |
| 别名 | SMAD4, SMAD Family Member 4, SMAD 4, Mothers Against DPP Homolog 4, Mothers Against Decapentaplegic Homolog 4, MADH4, MAD Homolog 4, hSMAD4, DPC4, Deletion Target in Pancreatic Carcinoma 4 |
| Ig Type | Rabbit IgG |
| 克隆号 | 7P892 |
| 交叉反应 | Human |
| 验证活性 | Western Blot -Positive WB detected in: Hela whole cell lysate, HEK293 whole cell lysate, MCF-7 whole cell lysate -All lanes: SMAD4 antibody at 1:500 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 61 kDa -Observed band size: 55-72 kDa |
| 应用 | ELISA, WB |
| 推荐剂量 | WB:1:500-1:2000. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Cytoplasm. Nucleus. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | In muscle physiology, plays a central role in the balance between atrophy and hypertrophy. When recruited by MSTN, promotes atrophy response via phosphorylated SMAD2/4. MSTN decrease causes SMAD4 release and subsequent recruitment by the BMP pathway to promote hypertrophy via phosphorylated SMAD1/5/8. Acts synergistically with SMAD1 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. Binds to SMAD binding elements (SBEs) (5'-GTCT/AGAC-3') within BMP response element (BMPRE) of cardiac activating regions. Common SMAD (co-SMAD) is the coactivator a... |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: Human SMAD4 |
| 抗原种属 | Human |
| 基因ID | 4089 |
| Uniprot ID | |
| 研究领域 | Epigenetics and Nuclear Signaling, Cancer, Cardiovascular, Metabolism, Signal transduction, Stem cells |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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