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Anti-FKBP51 Antibody (6E556)

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产品编号 TMAC-01490

别名 T cell FK506 binding protein, Rotamase, Ptg10, Ptg 10, PPIase FKBP5, PPIase, Peptidyl-prolyl cis-trans isomerase FKBP5, Peptidylprolyl cis trans isomerase, Peptidyl prolyl cis trans isomerase, P54, OTTHUMP00000016268, MGC111006, HSP90-binding immunophilin, HSP90 binding immunophilin, FKBP54, FKBP-51, FKBP5_HUMAN, FKBP-5, FKBP5, FKBP 54, FKBP 51, FKBP 5, FK506-binding protein 5, FK506 binding protein 5, FF1 antigen, Androgen-regulated protein 6, Androgen regulated protein 6, AIG6, AIG 6, 54 kDa progesterone receptor-associated immunophilin, 54 kDa progesterone receptor associated immunophilin, 51 kDa FKBP, 51 kDa FK506-binding protein, 51 kDa FK506 binding protein 5, 51 kDa FK506 binding protein

Anti-FKBP51 Antibody (6E556) 是一种 Rabbit 抗体，靶向 FKBP51。Anti-FKBP51 Antibody (6E556) 可用于 FCM,ICC/IF,IHC,IP,WB。

Anti-FKBP51 Antibody (6E556)

Anti-FKBP51 Antibody (6E556)

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Rating icon 还可以
产品编号 TMAC-01490 别名 T cell FK506 binding protein, Rotamase, Ptg10, Ptg 10, PPIase FKBP5, PPIase, Peptidyl-prolyl cis-trans isomerase FKBP5, Peptidylprolyl cis trans isomerase, Peptidyl prolyl cis trans isomerase, P54, OTTHUMP00000016268, MGC111006, HSP90-binding immunophilin, HSP90 binding immunophilin, FKBP54, FKBP-51, FKBP5_HUMAN, FKBP-5, FKBP5, FKBP 54, FKBP 51, FKBP 5, FK506-binding protein 5, FK506 binding protein 5, FF1 antigen, Androgen-regulated protein 6, Androgen regulated protein 6, AIG6, AIG 6, 54 kDa progesterone receptor-associated immunophilin, 54 kDa progesterone receptor associated immunophilin, 51 kDa FKBP, 51 kDa FK506-binding protein, 51 kDa FK506 binding protein 5, 51 kDa FK506 binding protein

Anti-FKBP51 Antibody (6E556) 是一种 Rabbit 抗体，靶向 FKBP51。Anti-FKBP51 Antibody (6E556) 可用于 FCM,ICC/IF,IHC,IP,WB。

规格价格库存数量
50 μL
¥ 1,495
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100 μL
¥ 2,495
5日内发货
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生物活性
产品描述
Anti-FKBP51 Antibody (6E556) is a Rabbit antibody targeting FKBP51. Anti-FKBP51 Antibody (6E556) can be used in FCM,ICC/IF,IHC,IP,WB.
别名T cell FK506 binding protein, Rotamase, Ptg10, Ptg 10, PPIase FKBP5, PPIase, Peptidyl-prolyl cis-trans isomerase FKBP5, Peptidylprolyl cis trans isomerase, Peptidyl prolyl cis trans isomerase, P54, OTTHUMP00000016268, MGC111006, HSP90-binding immunophilin, HSP90 binding immunophilin, FKBP54, FKBP-51, FKBP5_HUMAN, FKBP-5, FKBP5, FKBP 54, FKBP 51, FKBP 5, FK506-binding protein 5, FK506 binding protein 5, FF1 antigen, Androgen-regulated protein 6, Androgen regulated protein 6, AIG6, AIG 6, 54 kDa progesterone receptor-associated immunophilin, 54 kDa progesterone receptor associated immunophilin, 51 kDa FKBP, 51 kDa FK506-binding protein, 51 kDa FK506 binding protein 5, 51 kDa FK506 binding protein
Ig Type
IgG
克隆号
6E556
交叉反应
Human,Rat
验证活性
1. Western blot analysis of FKBP51 on rat kidney tissue and Daudi cell lysate using anti-FKBP51 antibody at 1/500 dilution.
2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-FKBP51 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-FKBP51 antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded rat lung tissue tissue using anti-FKBP51 antibody. Counter stained with hematoxylin.
5. Flow cytometric analysis of Daudi cells with FKBP51 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
verifiedActivityverifiedActivityverifiedActivityverifiedActivityverifiedActivity
应用FCMICC/IFIHCIPWB
推荐剂量
WB: 1:500-2000; IHC: 1:50-200; ICC/IF: 1:50-200; IP: 1:50; FCM: 1:50
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景The immunophilins are a highly conserved family of cis-trans peptidyl-prolyl isomerases that bind to and mediate the effects of immunosuppressive drugs, such as cyclosporin, FK506 and rapamycin. Several related immunophilins, FKBP12, FKBP51 and FKBP52, are characterized as cytosolic FK506-binding proteins, and following ligand binding, they functionally inhibit the phosphatase activity of calcineurin. The ubiquitously expressed FKBP12 also associates with the cytoplasmic domain of the TGFβ-type I receptor, where it stabilizes the inactive conformation of the receptor and blocks the activation of the TGFβ pathway. FKBP51 and FKBP52 are two highly related proteins. FKBP51 is predominantly expressed in T cells and is induced by glucocorticoids. FKBP51 mediates the effects of FK506 and rapamycin by inhibiting intracellular calcineurin activity, and by blocking T-cell activation and proliferation. FKBP52, known also as FKBP-59 or heat shock protein 56, is expressed in a variety of tissues and can also associate with the heat shock protein (hsp90) in mature steroid receptor complexes (6,8).
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
Q13451
化学信息
分子量Theoretical: 51 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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