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Anti-FKBP51 Antibody (6E556)
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产品编号 TMAC-01490
别名 T cell FK506 binding protein, Rotamase, Ptg10, Ptg 10, PPIase FKBP5, PPIase, Peptidyl-prolyl cis-trans isomerase FKBP5, Peptidylprolyl cis trans isomerase, Peptidyl prolyl cis trans isomerase, P54, OTTHUMP00000016268, MGC111006, HSP90-binding immunophilin, HSP90 binding immunophilin, FKBP54, FKBP-51, FKBP5_HUMAN, FKBP-5, FKBP5, FKBP 54, FKBP 51, FKBP 5, FK506-binding protein 5, FK506 binding protein 5, FF1 antigen, Androgen-regulated protein 6, Androgen regulated protein 6, AIG6, AIG 6, 54 kDa progesterone receptor-associated immunophilin, 54 kDa progesterone receptor associated immunophilin, 51 kDa FKBP, 51 kDa FK506-binding protein, 51 kDa FK506 binding protein 5, 51 kDa FK506 binding protein
Anti-FKBP51 Antibody (6E556) 是一种 Rabbit 抗体，靶向 FKBP51。Anti-FKBP51 Antibody (6E556) 可用于 WB,IHC,ICC/IF,IP,FCM。
Anti-FKBP51 Antibody (6E556)
Anti-FKBP51 Antibody (6E556)
还可以产品编号 TMAC-01490 别名 T cell FK506 binding protein, Rotamase, Ptg10, Ptg 10, PPIase FKBP5, PPIase, Peptidyl-prolyl cis-trans isomerase FKBP5, Peptidylprolyl cis trans isomerase, Peptidyl prolyl cis trans isomerase, P54, OTTHUMP00000016268, MGC111006, HSP90-binding immunophilin, HSP90 binding immunophilin, FKBP54, FKBP-51, FKBP5_HUMAN, FKBP-5, FKBP5, FKBP 54, FKBP 51, FKBP 5, FK506-binding protein 5, FK506 binding protein 5, FF1 antigen, Androgen-regulated protein 6, Androgen regulated protein 6, AIG6, AIG 6, 54 kDa progesterone receptor-associated immunophilin, 54 kDa progesterone receptor associated immunophilin, 51 kDa FKBP, 51 kDa FK506-binding protein, 51 kDa FK506 binding protein 5, 51 kDa FK506 binding protein
Anti-FKBP51 Antibody (6E556) 是一种 Rabbit 抗体，靶向 FKBP51。Anti-FKBP51 Antibody (6E556) 可用于 WB,IHC,ICC/IF,IP,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,495 | 5日内发货 | |
| 100 μL | ¥ 2,495 | 5日内发货 |
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| 产品描述 | Anti-FKBP51 Antibody (6E556) is a Rabbit antibody targeting FKBP51. Anti-FKBP51 Antibody (6E556) can be used in WB,IHC,ICC/IF,IP,FCM. |
| 别名 | T cell FK506 binding protein, Rotamase, Ptg10, Ptg 10, PPIase FKBP5, PPIase, Peptidyl-prolyl cis-trans isomerase FKBP5, Peptidylprolyl cis trans isomerase, Peptidyl prolyl cis trans isomerase, P54, OTTHUMP00000016268, MGC111006, HSP90-binding immunophilin, HSP90 binding immunophilin, FKBP54, FKBP-51, FKBP5_HUMAN, FKBP-5, FKBP5, FKBP 54, FKBP 51, FKBP 5, FK506-binding protein 5, FK506 binding protein 5, FF1 antigen, Androgen-regulated protein 6, Androgen regulated protein 6, AIG6, AIG 6, 54 kDa progesterone receptor-associated immunophilin, 54 kDa progesterone receptor associated immunophilin, 51 kDa FKBP, 51 kDa FK506-binding protein, 51 kDa FK506 binding protein 5, 51 kDa FK506 binding protein |
| Ig Type | IgG |
| 交叉反应 | Human,Rat |
| 验证活性 | 1. Western blot analysis of FKBP51 on rat kidney tissue and Daudi cell lysate using anti-FKBP51 antibody at 1/500 dilution. 2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-FKBP51 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-FKBP51 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded rat lung tissue tissue using anti-FKBP51 antibody. Counter stained with hematoxylin. 5. Flow cytometric analysis of Daudi cells with FKBP51 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody. |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000; IHC: 1:50-200; ICC/IF: 1:50-200; IP: 1:50; FCM: 1:50 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | The immunophilins are a highly conserved family of cis-trans peptidyl-prolyl isomerases that bind to and mediate the effects of immunosuppressive drugs, such as cyclosporin, FK506 and rapamycin. Several related immunophilins, FKBP12, FKBP51 and FKBP52, are characterized as cytosolic FK506-binding proteins, and following ligand binding, they functionally inhibit the phosphatase activity of calcineurin. The ubiquitously expressed FKBP12 also associates with the cytoplasmic domain of the TGFβ-type I receptor, where it stabilizes the inactive conformation of the receptor and blocks the activation of the TGFβ pathway. FKBP51 and FKBP52 are two highly related proteins. FKBP51 is predominantly expressed in T cells and is induced by glucocorticoids. FKBP51 mediates the effects of FK506 and rapamycin by inhibiting intracellular calcineurin activity, and by blocking T-cell activation and proliferation. FKBP52, known also as FKBP-59 or heat shock protein 56, is expressed in a variety of tissues and can also associate with the heat shock protein (hsp90) in mature steroid receptor complexes (6,8). |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 51 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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