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Anti-SATB2 Antibody (9F289)
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产品编号 TMAH-01071
别名 Special AT-rich sequence-binding protein 2, SATB 2, KIAA1034, DNA-binding protein SATB2
Anti-SATB2 Antibody (9F289) 是一种抗体，靶向 SATB2。Anti-SATB2 Antibody (9F289) 可用于 ELISA, IHC。
Anti-SATB2 Antibody (9F289)
Anti-SATB2 Antibody (9F289)
还可以产品编号 TMAH-01071 别名 Special AT-rich sequence-binding protein 2, SATB 2, KIAA1034, DNA-binding protein SATB2
Anti-SATB2 Antibody (9F289) 是一种抗体，靶向 SATB2。Anti-SATB2 Antibody (9F289) 可用于 ELISA, IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,310 | 5日内发货 | |
| 100 μL | ¥ 2,195 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-SATB2 Antibody (9F289) is an antibody targeting SATB2. Anti-SATB2 Antibody (9F289) can be used in ELISA, IHC. |
| 别名 | Special AT-rich sequence-binding protein 2, SATB 2, KIAA1034, DNA-binding protein SATB2 |
| Ig Type | Rabbit IgG |
| 克隆号 | 9F289 |
| 交叉反应 | Human |
| 验证活性 | IHC image of TMAH-01071 diluted at 1:50 and staining in paraffin-embedded human rectal cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.68% DAB. |
| 应用 | |
| 推荐剂量 | IHC:1:50-1:200. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Nucleus matrix. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Binds to DNA, at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcription factor controlling nuclear gene expression, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. Required for the initiation of the upper-layer neurons (UL1) specific genetic program and for the inactivation of deep-layer neurons (DL) and UL2 specific genes, probably by modulating BCL11B expression. Repressor of Ctip2 and regulatory determinant of corticocortical connections in the developing cerebral cortex. May play an important role in palate formation. Acts as a molecular node in a transcriptional network regulating skeletal development and osteoblast differentiation. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: Human SATB2 |
| 抗原种属 | Human |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | Epigenetics and Nuclear Signaling, Neuroscience |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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