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Anti-MFN2 Antibody (8I564)
还可以产品编号 TMAH-00753
Anti-MFN2 Antibody (8I564) 是一种抗体，靶向 MFN2。Anti-MFN2 Antibody (8I564) 可用于 ELISA, IHC。
Anti-MFN2 Antibody (8I564)
Anti-MFN2 Antibody (8I564)
还可以产品编号 TMAH-00753
Anti-MFN2 Antibody (8I564) 是一种抗体，靶向 MFN2。Anti-MFN2 Antibody (8I564) 可用于 ELISA, IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,310 | 5日内发货 | |
| 100 μL | ¥ 2,180 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-MFN2 Antibody (8I564) is an antibody targeting MFN2. Anti-MFN2 Antibody (8I564) can be used in ELISA, IHC. |
| Ig Type | Rabbit IgG |
| 克隆号 | 8I564 |
| 交叉反应 | Human |
| 验证活性 | IHC image of TMAH-00753 diluted at 1:100 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. |
| 应用 | ELISA, IHC |
| 推荐剂量 | IHC:1:50-1:200. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Mitochondrion outer membrane; Multi-pass membrane protein. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion. Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events. Overexpression induces the formation of mitochondrial networks. Membrane clustering requires GTPase activity and may involve a major rearrangement of the coiled coil domains (Probable). Plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. Plays an important role in the regulation of vascular smooth muscle cell proliferation. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy). Is required for PRKN recruitment to dysfunctional mitochondria. Involved in the control of unfolded protein response (UPR) upon ER stress including activation of apoptosis and autophagy during ER stress. Acts as an upstream regulator of EIF2AK3 and suppresses EIF2AK3 activation under basal conditions. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: Human Mitofusin 2 |
| 抗原种属 | Human |
| 基因ID | 9927 |
| Uniprot ID | |
| 研究领域 | Neuroscience, Cancer, Cell biology, Tags & Cell Markers, Metabolism, Signal transduction |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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