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HLA-G Free Heavy Chain Protein, Human, Recombinant (His & Avi)

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产品编号 TMPK-00836

HLA-G is a molecule that was first known to confer protection to the fetus from destruction by the immune system of its mother, thus critically contributing to fetal-maternal tolerance. The first functional finding constituted the basis for HLA-G research and can be summarized as such: HLA-G, membrane-bound or soluble, strongly binds its inhibitory receptors on immune cells (NK, T, B, monocytes/dendritic cells), inhibits the functions of these effectors, and so induces immune inhibition.

HLA-G Free Heavy Chain Protein, Human, Recombinant (His & Avi)

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产品编号 TMPK-00836

规格	价格	库存
5 μg	¥ 268	6-8日内发货
10 μg	¥ 419	6-8日内发货
20 μg	¥ 678	5日内发货
50 μg	¥ 1,320	5日内发货
100 μg	¥ 2,210	5日内发货
200 μg	¥ 3,930	5日内发货
500 μg	¥ 8,900	5日内发货

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产品信息

生物活性	Immobilized Human HLA-G Free Heavy Chain, His Tag at 2μg/ml (100μl/Well) on the. Dose response curve for Anti-HLA-G Antibody, hFc Tag with the EC50 of 25.9ng/ml determined by ELISA.
产品描述	HLA-G is a molecule that was first known to confer protection to the fetus from destruction by the immune system of its mother, thus critically contributing to fetal-maternal tolerance. The first functional finding constituted the basis for HLA-G research and can be summarized as such: HLA-G, membrane-bound or soluble, strongly binds its inhibitory receptors on immune cells (NK, T, B, monocytes/dendritic cells), inhibits the functions of these effectors, and so induces immune inhibition.
种属	Human
表达系统	E. coli
标签	C-His-Avi
蛋白编号	P17693-1
别名	sHLA-G,MHC-G,MHC class Ib antigen,MHC Class I Antigen G,HLA-G,HLAG,HLA G antigen,HLA G,b2 microglobulin
蛋白构建	Gly25-Thr305(C66S)
蛋白纯度	> 95% as determined by Tris-Bis PAGE
分子量	35.5 kDa (predicted). The protein migrates to 36-40 kDa based on Tris-Bis PAGE result.
内毒素	< 1 EU/μg by the LAL method.
蛋白性状	Solution
缓冲液	Supplied as 0.22 μm filtered solution in 20 mM Tris, 500 mM NaCl, 20% Glycerol (pH 8.0).
存储	It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	HLA-G is a molecule that was first known to confer protection to the fetus from destruction by the immune system of its mother, thus critically contributing to fetal-maternal tolerance. The first functional finding constituted the basis for HLA-G research and can be summarized as such: HLA-G, membrane-bound or soluble, strongly binds its inhibitory receptors on immune cells (NK, T, B, monocytes/dendritic cells), inhibits the functions of these effectors, and so induces immune inhibition.