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GBA Protein, Mouse, Recombinant (His & SUMO)

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产品编号 TMPH-02771

GBA Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli.

GBA Protein, Mouse, Recombinant (His & SUMO)

一键复制产品信息

产品编号 TMPH-02771

GBA Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli.

规格	价格	库存
5 μg	¥ 656	20日内发货
10 μg	¥ 1,070	20日内发货
20 μg	¥ 1,800	20日内发货
50 μg	¥ 2,730	20日内发货
100 μg	¥ 3,760	20日内发货
200 μg	¥ 5,780	20日内发货
500 μg	¥ 9,870	20日内发货
1 mg	¥ 16,000	20日内发货

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产品信息

生物活性	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
产品描述	GBA Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli.
种属	Mouse
表达系统	E. coli
标签	N-6xHis-SUMO
蛋白编号	P17439
别名	Lysosomal glycosylceramidase,Lysosomal galactosylceramidase,Lysosomal cholesterol glycosyltransferase,Lysosomal acid glucosylceramidase,Lysosomal acid GCase,Gba1,Gba,D-glucosyl-N-acylsphingosine glucohydrolase,Cholesteryl-beta-glucosidase,Cholesterol glucosyltransferase (SGTase),Beta-glucocerebrosidase,Acid beta-glucosidase
氨基酸序列	AQPCIPKSFGYSSVVCVCNASYCDSLDPVTLPALGTFSRYESTRRGRRMELSVGAIQANRTGTGLLLTLQPEKKFQKVKGFGGAMTDATALNILALSPPTQKLLLRSYFSTNGIEYNIIRVPMASCDFSIRVYTYADTPNDFQLSNFSLPEEDTKLKIPLIHQALKMSSRPISLFASPWTSPTWLKTNGRVNGKGSLKGQPGDIFHQTWANYFVKFLDAYAKYGLRFWAVTAENEPTAGLFTGYPFQCLGFTPEHQRDFISRDLGPALANSSHDVKLLMLDDQRLLLPRWAEVVLSDPEAAKYVHGIAVHWYMDFLAPAKATLGETHRLFPNTMLFASEACVGSKFWEQSVRLGSWDRGMQYSHSIITNLLYHVTGWTDWNLALNPEGGPNWVRNFVDSPIIVDIPKDAFYKQPMFYHLGHFSKFIPEGSQRVALVASESTDLETVALLRPDGSAVVVVLNRSSEDVPLTISDPDLGFLETVSPGYSIHTYLWRRQ
蛋白构建	20-515 aa
蛋白纯度	> 85% as determined by SDS-PAGE.
分子量	71.5 kDa (predicted)
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液	Tris-based buffer, 50% glycerol
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Glucosylceramidase that catalyzes, within the lysosomal compartment, the hydrolysis of glucosylceramide/GlcCer into free ceramide and glucose. Thereby, plays a central role in the degradation of complex lipids and the turnover of cellular membranes. Through the production of ceramides, participates in the PKC-activated salvage pathway of ceramide formation. Also plays a role in cholesterol metabolism. May either catalyze the glucosylation of cholesterol, through a transglucosylation reaction that transfers glucose from glucosylceramide to cholesterol. The short chain saturated C8:0-GlcCer and the mono-unsaturated C18:0-GlcCer being the most effective glucose donors for that transglucosylation reaction. Under specific conditions, may alternatively catalyze the reverse reaction, transferring glucose from cholesteryl-beta-D-glucoside to ceramide. Finally, may also hydrolyze cholesteryl-beta-D-glucoside to produce D-glucose and cholesterol.