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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-PDE7B Polyclonal Antibody

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货号 TMAB-10115

Anti-PDE7B Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PDE7B。Anti-PDE7B Polyclonal Antibody 可用于 WB。

Anti-PDE7B Polyclonal Antibody

Anti-PDE7B Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-10115

Anti-PDE7B Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PDE7B。Anti-PDE7B Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-PDE7B Polyclonal Antibody is a Rabbit antibody targeting PDE7B. Anti-PDE7B Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
组织特异性Highly expressed in brain. Also expressed in heart, liver, skeletal muscle and pancreas.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Phosphodiesterases (PDE, also designated cyclic nucleotide phosphodiesterase) are important for the downregulation of the intracellular level of the second messenger cyclic adenosine monophosphate (cAMP) by hydrolyzing cAMP to 5'AMP. Phosphodiesterase type 3 isoforms, PDE3A and 3B, are expressed primarily in cardiovascular tissue and adipose tissue, respectively. PDE3A, is found in myocardium and platelets and PDE3B is found in lymphocytes. The PDE7A1 (HCP1) isozyme and the PDE7A2 proteins, alternate splice products of PDE7A, are highly expressed in skeletal muscle. PDE7B is most highly expressed in pancreas. The PDE family contains proteins that serve tissue-specific roles in regulation of lipolysis, glycogenolysis, myocardial contractility, and smooth muscle relaxation.
抗原信息
免疫原
KLH conjugated synthetic peptide: human PDE7B
抗原种属
Human
基因名称
PDE7B
基因ID
27115
蛋白名称
cAMP-specific 3', 5'-cyclic phosphodiesterase 7B
Uniprot ID
Q9NP56
功能
PDE7B is a cAMP specific phosphodiesterase. The cAMP-specific phosphodiesterase type-7 (PDE7) family is comprised of 2 genes (PDE7A and PDE7B) each with multiple splice variants generated by RNA splicing and use of alternate initiation sites. PDE7B has three splice variants (PDE7B1 = 446 amino acid; PDE7B2 =359 amino acids and PDE7B3 = 459 amino acids. Both PDE7B2 ad PDE7B3 posses unique N-terminal sequences. PDE7B is expressed in various tissues including skeletal muscle, heart, lung and testis. PDE7B may be involved in the control of cAMP-mediated neural activity and cAMP metabolism in the brain.
化学信息
分子量Theoretical: 52 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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