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Anti-NEDD4L Antibody (2B935)
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产品编号 TMAC-02767
别名 NEDL3, NEDD4L, Nedd4-2, NEDD4.2, KIAA0439, HECT-type E3 ubiquitin transferase NED4L, E3 ubiquitin-protein ligase NEDD4-like
Anti-NEDD4L Antibody (2B935) 是一种 Rabbit 抗体，靶向 NEDD4L。Anti-NEDD4L Antibody (2B935) 可用于 WB,IP。
Anti-NEDD4L Antibody (2B935)
Anti-NEDD4L Antibody (2B935)
还可以产品编号 TMAC-02767 别名 NEDL3, NEDD4L, Nedd4-2, NEDD4.2, KIAA0439, HECT-type E3 ubiquitin transferase NED4L, E3 ubiquitin-protein ligase NEDD4-like
Anti-NEDD4L Antibody (2B935) 是一种 Rabbit 抗体，靶向 NEDD4L。Anti-NEDD4L Antibody (2B935) 可用于 WB,IP。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,495 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
化学信息
| 产品描述 | Anti-NEDD4L Antibody (2B935) is a Rabbit antibody targeting NEDD4L. Anti-NEDD4L Antibody (2B935) can be used in WB,IP. |
| 别名 | NEDL3, NEDD4L, Nedd4-2, NEDD4.2, KIAA0439, HECT-type E3 ubiquitin transferase NED4L, E3 ubiquitin-protein ligase NEDD4-like |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 应用 | |
| 推荐剂量 | WB: 1:1000-5000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | NEDD4-L (neural precursor cell expressed, developmentally down-regulated 4-like), also known as RSP5, NEDD4-2 or NEDL3, is a 975 amino acid protein that localizes to the cytoplasm and contains four WW domains, one HECT domain and one C2 domain. Expressed ubiquitously with highest expression in pancreas, prostate and kidney, NEDD4-L functions as an E3 ubiquitin-protein ligase that, characteristic of E3 ligase proteins, accepts ubiquitin (in the form of a thioester) from an E2 ubiquitin-conjugating enzyme and transfers that ubiquitin residue to substrates targeted for degradation. Through its ability to ubiquitinate and induce the proteasome-dependent degradation of proteins such as Smad2 and TGFβ RII, NEDD4-L is thought to inhibit the TGFβ signaling pathway, thereby regulating the signaling pathways that control cell growth and differentiation. NEDD4-L is expressed as eight isoforms due to alternative splicing events. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 112 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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