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Anti-Insulin Antibody (7U822)
还可以产品编号 TMAY-01502
Anti-Insulin Antibody (7U822) 是一种 Mouse 抗体，靶向 Insulin。Anti-Insulin Antibody (7U822) 可用于 IHC-P。
Anti-Insulin Antibody (7U822)
Anti-Insulin Antibody (7U822)
还可以产品编号 TMAY-01502
Anti-Insulin Antibody (7U822) 是一种 Mouse 抗体，靶向 Insulin。Anti-Insulin Antibody (7U822) 可用于 IHC-P。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Insulin Antibody (7U822) is a Mouse antibody targeting Insulin. Anti-Insulin Antibody (7U822) can be used in IHC-P. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 7U822 |
| 交叉反应 | Human, Cynomolgus, Mouse, Rat |
| 验证活性 | 1. Immunochemical staining Insulin in human pancreas with mouse monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 2. Immunochemical staining Insulin in cynomolgus pancreas with mouse monoclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections. 3. Immunochemical staining Insulin in rat pancreas with mouse monoclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections. 4. Immunochemical staining Insulin in mouse pancreas with mouse monoclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections. |
| 应用 | IHC-P |
| 推荐剂量 | IHC-P: 1:100-1:500 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Insulin / INS (rh Insulin / INS; TMPY-00395; P01308; Phe25-Lys53 & Gly90-Asn110). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | INS (Insulin) is a Protein Coding gene. This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. The binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Diseases associated with INS include Hyperproinsulinemia and Maturity-Onset Diabetes Of The Young, Type 10. A multitude of mutant alleles with phenotypic effects has been identified, including insulin-dependent diabetes mellitus, permanent neonatal diabetes mellitus, maturity-onset diabetes of the young type 10, and hyperproinsulinemia.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human Insulin / INS Protein (TMPY-00395) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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