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Anti-EphB2 Polyclonal Antibody 2

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货号 TMAB-05621

Anti-EphB2 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 EphB2。Anti-EphB2 Polyclonal Antibody 2 可用于 WB,FCM。

Anti-EphB2 Polyclonal Antibody 2

Anti-EphB2 Polyclonal Antibody 2

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Rating icon 还可以
货号 TMAB-05621

Anti-EphB2 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 EphB2。Anti-EphB2 Polyclonal Antibody 2 可用于 WB,FCM。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-EphB2 Polyclonal Antibody 2 is a Rabbit antibody targeting EphB2. Anti-EphB2 Polyclonal Antibody 2 can be used in WB,FCM.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Chicken,Dog,Cow)
应用WBFCM
推荐剂量
WB: 1:500-2000; FCM: 3μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Single-pass type I membrane protein. Cell projection, axon. Cell projection, dendrite.
组织特异性Brain, heart, lung, kidney, placenta, pancreas, liver and skeletal muscle. Preferentially expressed in fetal brain.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a transmembrane region and an intracellular kinase domain. They bind ligands called ephrins and are involved in diverse cellular processes including motility, division, and differentiation. A distinguishing characteristic of Eph-ephrin signaling is that both receptors and ligands are competent to transduce a signaling cascade, resulting in bidirectional signaling. This protein belongs to a subgroup of the Eph receptors called EphB. Proteins of this subgroup are distinguished from other members of the family by sequence homology and preferential binding affinity for membrane-bound ephrin-B ligands. Allelic variants are associated with prostate and brain cancer susceptibility. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015]
抗原信息
免疫原
KLH conjugated synthetic peptide: human EPHB2
抗原种属
Human
基因名称
EPHB2
基因ID
2048
蛋白名称
Ephrin type-B receptor 2
Uniprot ID
P29323
功能
Receptor for members of the ephrin-B family. Phosphorylates ARHGEF15, leading to its ubiquitination and degradation by the proteasome which promotes EFNB1-dependent synapse formation. Can function in aspects of retinal ganglion cell axon guidance to the optic disk even when lacking its tyrosine kinase domain. Acts as a tumor suppressor.
化学信息
分子量Theoretical: 108 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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