Anti-BTC Antibody (7D630)

Name: Anti-BTC Antibody (7D630)
Brand: TargetMol
SKU: TMAB-03244
Rating: 4.5 (1 reviews)

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货号 TMAB-03244

Anti-BTC Antibody (7D630) 是一种 Mouse 抗体，靶向 BTC。Anti-BTC Antibody (7D630) 可用于 WB,ICC/IF。

Anti-BTC Antibody (7D630)

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货号 TMAB-03244

Anti-BTC Antibody (7D630) 是一种 Mouse 抗体，靶向 BTC。Anti-BTC Antibody (7D630) 可用于 WB,ICC/IF。

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生物活性

产品描述	Anti-BTC Antibody (7D630) is a Mouse antibody targeting BTC. Anti-BTC Antibody (7D630) can be used in WB,ICC/IF.
Ig Type	IgG1, Kappa
克隆号	7D630
反应种属	Human
应用	WB ICC/IF
推荐剂量	WB: 1:500-2000; ICC/IF: 1:50-200
抗体种类	Monoclonal
宿主来源	Mouse
亚细胞定位	Cell membrane and Secreted > extracellular space.
组织特异性	Synthesized in several tissues and tumor cells. Predominantly expressed in pancreas and small intestine.
构建方式	Recombinant Antibody
纯化方式	Protein G purified
性状	Liquid
缓冲液	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度	1mg/ml
研究背景	Betacellulin (BTC), a member of the epidermal growth factor (EGF) family, was originally identified as a growth-promoting factor in the conditioned medium of a mouse pancreatic-cell carcinoma (insulinoma) cell line and has since been identified in humans. BTC is synthesized as a large transmembrane precursor molecule that can be cleaved proteolytically to release the soluble form of BTC or function as membrane-anchored growth factors in juxtacrine signaling. BTC, in addition to stimulating homodimers of ErbB-1 and ErbB-4, is capable of binding and activating all possible combinations of heterodimeric ErbB receptors including the oncogenic ErbB-2/ErbB-3 complex. BTC is also expressed in some human malignancies and may have an important role in tumor growth progression.

抗原信息

基因名称	BTC
基因ID	685
蛋白名称	Probetacellulin
功能	Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. The effects of betacellulin are probably mediated by the EGF receptor and other related receptors.

储存&溶解度

储存方式	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式	Shipping with blue ice.
存储	store at low temperature \| -20°C for 1 year