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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-EIF4E2 Polyclonal Antibody

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货号 TMAB-05519

Anti-EIF4E2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 EIF4E2。Anti-EIF4E2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-EIF4E2 Polyclonal Antibody

Anti-EIF4E2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-05519

Anti-EIF4E2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 EIF4E2。Anti-EIF4E2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-EIF4E2 Polyclonal Antibody is a Rabbit antibody targeting EIF4E2. Anti-EIF4E2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Dog,Pig,Cow,Horse,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The initiation of protein synthesis in eukaryotic cells is regulated by interactions between protein initiation factors and RNA molecules. The eukaryotic initiation factor 4E family (eIF4E) is comprised of three proteins that are involved in the early initiation of protein synthesis. eIF4E2 (eukaryotic translation initiation factor 4E family member 2), also known as 4EHP, IF4e, 4E-LP or EIF4EL3, is a ubiquitously expressed 245 amino acid protein. During early translation events, eIF4E2 recognizes and binds the 7-methylguanosine-containing mRNA cap (a cotranscriptionally added structure that conveys mRNA stability and allows for efficient RNA processing), thus initiating the unwinding of mRNA secondary structures and facilitating mRNA-ribosome binding. eIF4E2 competes with eIF4E (member 1) for cap binding and, upon modification by the ubiquitin-like protein ISG15 (Interferon-induced 15 kDa protein), exhibits increased mRNA cap affinity.
抗原信息
免疫原
KLH conjugated synthetic peptide: human EIF4EL3
抗原种属
Human
基因名称
EIF4E2
基因ID
9470
蛋白名称
Eukaryotic translation initiation factor 4E type 2
Uniprot ID
O60573
功能
Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.
化学信息
分子量Theoretical: 28 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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