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Anti-AFAP1L2 Polyclonal Antibody

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货号 TMAB-02373

Anti-AFAP1L2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 AFAP1L2。Anti-AFAP1L2 Polyclonal Antibody 可用于 WB,FCM。

Anti-AFAP1L2 Polyclonal Antibody

Anti-AFAP1L2 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-02373

Anti-AFAP1L2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 AFAP1L2。Anti-AFAP1L2 Polyclonal Antibody 可用于 WB,FCM。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍


生物活性
产品描述
Anti-AFAP1L2 Polyclonal Antibody is a Rabbit antibody targeting AFAP1L2. Anti-AFAP1L2 Polyclonal Antibody can be used in WB,FCM.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat)
应用WBFCM
推荐剂量
WB: 1:500-2000; FCM: 2μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm.
组织特异性Detected in spleen and thyroid, and at lower levels in kidney, brain, lung and pancreas.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Actin filament associated protein (AFAP-110) interacts directly with actin filaments through its C-terminal actin-binding domain. AFAP-110 contains additional protein-binding domains as well, and serves as an adaptor protein. By linking signaling molecules to actin filaments, AFAP-110 provides a platform for the preparation of larger signaling complexes, activates Src kinases in response to cellular signals and also directly affects Actin organization as an Actin filament cross-linking protein. AFAP-1L2 (Actin filament-associated protein 1-like 2), also known as XB130, is a 818 amino acid cytoplasmic protein that contains two Pleckstrin homology (PH) domains, which are normally found in proteins involved in intracellular signaling. Like its relative AFAP110, AFAP-1L2 interacts with Src kinase and may play a role in Src-regulated transcription activation. AFAP-1L2 is expressed in thyroid and spleen and can also be detected at lower levels in lung, brain, pancreas and kidney. There are four isoforms of AFAP-1L2 that are produced as a result of alternative splicing events.
抗原信息
免疫原
KLH conjugated synthetic peptide: human AFAP1L2
抗原种属
Human
基因名称
AFAP1L2
基因ID
蛋白名称
Actin filament-associated protein 1-like 2
Uniprot ID
功能
May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation.
化学信息
分子量Theoretical: 90 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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