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Anti-AFAP1L2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 AFAP1L2。Anti-AFAP1L2 Polyclonal Antibody 可用于 WB,FCM。
Anti-AFAP1L2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 AFAP1L2。Anti-AFAP1L2 Polyclonal Antibody 可用于 WB,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,175 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
| 产品描述 | Anti-AFAP1L2 Polyclonal Antibody is a Rabbit antibody targeting AFAP1L2. Anti-AFAP1L2 Polyclonal Antibody can be used in WB,FCM. |
| Ig Type | IgG |
| 反应种属 | Mouse (predicted:Human,Rat) |
| 应用 | WBFCM |
| 推荐剂量 | WB: 1:500-2000; FCM: 2μg/Test |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm. |
| 组织特异性 | Detected in spleen and thyroid, and at lower levels in kidney, brain, lung and pancreas. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Actin filament associated protein (AFAP-110) interacts directly with actin filaments through its C-terminal actin-binding domain. AFAP-110 contains additional protein-binding domains as well, and serves as an adaptor protein. By linking signaling molecules to actin filaments, AFAP-110 provides a platform for the preparation of larger signaling complexes, activates Src kinases in response to cellular signals and also directly affects Actin organization as an Actin filament cross-linking protein. AFAP-1L2 (Actin filament-associated protein 1-like 2), also known as XB130, is a 818 amino acid cytoplasmic protein that contains two Pleckstrin homology (PH) domains, which are normally found in proteins involved in intracellular signaling. Like its relative AFAP110, AFAP-1L2 interacts with Src kinase and may play a role in Src-regulated transcription activation. AFAP-1L2 is expressed in thyroid and spleen and can also be detected at lower levels in lung, brain, pancreas and kidney. There are four isoforms of AFAP-1L2 that are produced as a result of alternative splicing events. |
| 免疫原 | KLH conjugated synthetic peptide: human AFAP1L2 |
| 抗原种属 | Human |
| 基因名称 | AFAP1L2 |
| 基因ID | |
| 蛋白名称 | Actin filament-associated protein 1-like 2 |
| Uniprot ID | |
| 功能 | May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation. |
| 分子量 | Theoretical: 90 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |