购物车
- 全部删除
- 您的购物车当前为空
Anti-REG1B Antibody (8C249) 是一种 Rabbit 抗体,靶向 REG1B。Anti-REG1B Antibody (8C249) 可用于 ELISA。
Anti-REG1B Antibody (8C249) 是一种 Rabbit 抗体,靶向 REG1B。Anti-REG1B Antibody (8C249) 可用于 ELISA。
产品描述 | Anti-REG1B Antibody (8C249) is a Rabbit antibody targeting REG1B. Anti-REG1B Antibody (8C249) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 8C249 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human REG1B (rh REG1B; TMPY-01394; NP_006498.1; Met 1-Asn 166). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Regenerating gene (Reg), first isolated from a regenerating islet cDNA library, encodes a secretory protein with a growth stimulating effect on pancreatic beta cells, and could be associated with fibrocalculous pancreatopathy. Reg and Reg-related genes which were expressed in various organs have been revealed to constitute a multigene family, the Reg family consisting of four subtypes (types I, II, III, IV) and are involved in cancers and neurodegenerative diseases. Regenerating islet-derived 1 beta (REG1B), also known as Lithostathine-1-beta and Pancreatic stone protein 2 (PSPS2), is a types I Reg protein and contains one typical C-type lectin domain. REG1B is a 166-amino acid protein that has 22 amino acid substitutions in comparison with the previously isolated human REG1A, and it is was expressed only in pancreas. REG1B Is normally found in the exocrine pancreas, whereas in other tissues it appears either only under pathological conditions, such as Alzheimer's disease (brain), cancer (colon), or during regeneration such as neuronal sprouting in brain and pancreas regeneration. REG1B might act as an inhibitor of spontaneous calcium carbonate precipitation. The REG1A and REG1B gene and proteins could play different roles in the pancreas. |
偶联 | Unconjugated |
免疫原 | Recombinant Human REG1B protein (TMPY-01394) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
评论内容