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Anti-CDNF Antibody (9D614)
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产品编号 TMAY-02801
别名 cerebral dopamine neurotrophic factor, Armetl1, 9330140G23
Anti-CDNF Antibody (9D614) 是一种 Mouse 抗体，靶向 CDNF。Anti-CDNF Antibody (9D614) 可用于 ELISA。
Anti-CDNF Antibody (9D614)
Anti-CDNF Antibody (9D614)
还可以产品编号 TMAY-02801 别名 cerebral dopamine neurotrophic factor, Armetl1, 9330140G23
Anti-CDNF Antibody (9D614) 是一种 Mouse 抗体，靶向 CDNF。Anti-CDNF Antibody (9D614) 可用于 ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 1,679 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-CDNF Antibody (9D614) is a Mouse antibody targeting CDNF. Anti-CDNF Antibody (9D614) can be used in ELISA. |
| 别名 | cerebral dopamine neurotrophic factor, Armetl1, 9330140G23 |
| Ig Type | Mouse IgG2b |
| 克隆号 | 9D614 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CDNF / ARMETL1 (rh CDNF / ARMETL1; TMPY-00568; NP_001025125.2; Met1-Leu187). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Cerebral Dopamine Neurotrophic Factor (CDNF), also known as ARMETL1 (ARMET-like protein 1), is a secreted protein with eight conserved cysteine residues, predicting a unique protein fold and defining a new, evolutionarily conserved protein family. CDNF is a novel neurotrophic factor with strong trophic activity on dopaminergic neurons comparable to that of glial cell line-derived neurotrophic factor (GDNF). CDNF/ARMETL1 is a evolutionary conserved protein which can protect and restore the function of dopaminergic neurons in the rat model of Parkinson's disease, suggesting that CDNF might be beneficial for the treatment of Parkinson's disease. CDNF is widely expressed in neurons in several brain regions including cerebral cortex, hippocampus, substantia nigra, striatum and cerebellum. Human CDNF is glycosylated and secreted from transiently transfected cells. CDNF promotes the survival, growth, and function of dopamine-specific neurons and is expressed in brain regions that undergo cocaine-induced neuroplasticity. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human CDNF / ARMETL1 Protein (TMPY-00568) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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