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YKL-40/CHI3L1 Protein, Mouse, Recombinant (His)

YKL-40/CHI3L1 Protein, Mouse, Recombinant (His)

产品编号 TMPY-02500
别名: Gp39, AW208766, Brp39, chitinase 3 like 1

YKL-40/CHI3L1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.3 kDa and the accession number is Q61362-2.

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YKL-40/CHI3L1 Protein, Mouse, Recombinant (His)
规格 价格/CNY 货期 数量
100 μg ¥ 3,820 现货
200 μg ¥ 6,750 5日内发货
500 μg ¥ 14,280 5日内发货
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产品目录号及名称: YKL-40/CHI3L1 Protein, Mouse, Recombinant (His) (TMPY-02500)
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生物活性 Testing in progress
产品描述 YKL-40/CHI3L1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.3 kDa and the accession number is Q61362-2.
种属 Mouse
表达系统 HEK293 Cells
标签 C-His
蛋白编号 Q61362-2
别名 Gp39, AW208766, Brp39, chitinase 3 like 1
蛋白构建 The extracellular domain of Mouse CHI3L1 (Q61362-2) (Met 1-Ala 381) was expressed, with a C-terminal polyhistidine tag.
蛋白纯度 > 97 % as determined by SDS-PAGE

TargetMol

分子量 42.3 kDa (predicted)
内毒素 < 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice.

研究背景 Chitinase-3-like protein 1 (CHI3L1) is a secreted heparin-binding glycoprotein whose expression is associated with vascular smooth muscle cell migration. CHI3L1 is expressed at high levels in postconfluent nodular VSMC cultures and at low levels in subconfluent proliferating cultures. CHI3L1 is a tissue-restricted, chitin-binding lectin and member of glycosyl hydrolase family 18. In contrast to many other monocyto / macrophage markers, its expression is absent in monocytes and strong induced during late stages of human macrophage differentiation. Elevated levels of CHI3L1 are associated with disorders exhibiting increased connective tissue turnover, such as rheum atoid, arthritis, osteoarthritis, scleroderma, and cirrhosis of liver, but is produced in cartilage from old donors or patiens with osteoarthritis. CHI3L1 is abnormally expressed in the hippocampus of subjects with schizophrenia and may be involved in the cellular response to various environmental events that are reported to increase the risk of schizophrenia.

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Keywords

YKL-40/CHI3L1 Protein, Mouse, Recombinant (His) AW-208766 Gp39 AW208766 AW 208766 Brp39 chitinase 3 like 1 recombinant recombinant-proteins proteins protein

 

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