购物车
全部删除
  • TargetMol
    您的购物车当前为空
前往下单页继续购物
顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-NCK1 Antibody (6C498)

一键复制产品信息
Rating icon 还可以
货号 TMAB-09278

Anti-NCK1 Antibody (6C498) 是一种 Rabbit 抗体，靶向 NCK1。Anti-NCK1 Antibody (6C498) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM。

Anti-NCK1 Antibody (6C498)

Anti-NCK1 Antibody (6C498)

一键复制产品信息
Rating icon 还可以
货号 TMAB-09278

Anti-NCK1 Antibody (6C498) 是一种 Rabbit 抗体，靶向 NCK1。Anti-NCK1 Antibody (6C498) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM。

规格价格库存数量
50 μL
¥ 1,380
5日内发货
100 μL
¥ 2,480
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
大包装 & 定制
加入购物车
TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
查看更多
资源下载:
产品操作手册

产品介绍

生物活性
产品描述
Anti-NCK1 Antibody (6C498) is a Rabbit antibody targeting NCK1. Anti-NCK1 Antibody (6C498) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM.
Ig Type
IgG
克隆号
6C498
反应种属
Human,Mouse,Rat
应用WBIHC-PIHC-FrICC/IFIFFCM
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-200; IHC-Fr: 1:100-200; ICC/IF: 1:50-200; IF: 1:100-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Endoplasmic reticulum. Nucleus. Note=Mostly cytoplasmic, but shuttles between the cytoplasm and the nucleus. Import into the nucleus requires the interaction with SOCS7. Predominantly nuclear following genotoxic stresses, such as UV irradiation, hydroxyurea or mitomycin C treatments.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.02% Proclin300.
浓度1mg/ml
研究背景Nck is a highly conserved, oncogenic protein. It is a common target for the action of different surface receptors, encoding one SH2 and three SH3 domains, the Src homology motifs found in nonreceptor tyrosine kinases, Ras GTPase activating protein, phosphatidylinositol 3 kinase, and phospholipase Cg. Nck is widely expressed in various tissues and in cell lines from human, murine, and rat origins. Nck is phosphorylated on tyrosine, serine, and threonine residues in response to stimulation of EGF and PDGF in A431 and NIH 3T3 cells respectively. Like other SH2 containing proteins, Nck is associated with tyrosine autophosphorylated EGF or PDGF receptors via its SH2 domain. Overexpression of Nck leads to transformation of NIH 3T3 cells.
抗原信息
免疫原
KLH conjugated synthetic peptide: human NCK1
抗原种属
Human
基因名称
NCK1
基因ID
4690
蛋白名称
Cytoplasmic protein NCK1
Uniprot ID
P16333
功能
Adapter protein which associates with tyrosine-phosphorylated growth factor receptors, such as KDR and PDGFRB, or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in the DNA damage response, not in the detection of the damage by ATM/ATR, but for efficient activation of downstream effectors, such as that of CHEK2. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling.
化学信息
分子量Theoretical: 25 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

  • 稀释 计算器
Related Tags: buy Anti-NCK1 Antibody (6C498) | purchase Anti-NCK1 Antibody (6C498) | Anti-NCK1 Antibody (6C498) cost | order Anti-NCK1 Antibody (6C498) | Anti-NCK1 Antibody (6C498) molecular weight