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别名 Beta-2 adrenoreceptor, Beta-2 adrenoceptor, Beta-2 adrenergic receptor, B2AR, ADRB2R, ADRB 2
Anti-ADRB2 Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 ADRB2。Anti-ADRB2 Polyclonal Antibody 2 可用于 WB。
Anti-ADRB2 Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 ADRB2。Anti-ADRB2 Polyclonal Antibody 2 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
| 产品描述 | Anti-ADRB2 Polyclonal Antibody 2 is a Rabbit antibody targeting ADRB2. Anti-ADRB2 Polyclonal Antibody 2 can be used in WB. |
| 别名 | Beta-2 adrenoreceptor, Beta-2 adrenoceptor, Beta-2 adrenergic receptor, B2AR, ADRB2R, ADRB 2 |
| Ig Type | IgG |
| 反应种属 | Human,Mouse,Rat (predicted:Dog,Horse,Sheep) |
| 验证活性 | Sample: Lane 1: Heart (Mouse) Lysate at 40 μg Lane 2: Stomach (Mouse) Lysate at 40 μg Lane 3: Heart (Rat) Lysate at 40 μg Lane 4: A431 (Human) Cell Lysate at 30 μg Primary: Anti-ADRB2 (TMAB-00071) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 55 kDa Observed band size: 50 kDa ![]() |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. Note=Colocalizes with VHL at the cell membrane. |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1 mg/mL |
| 研究背景 | Beta 2 Adrenergic Receptor is a member of the G protein coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L type calcium channel Ca(V)1.2. This receptor channel complex also contains a G protein, an adenylyl cyclase, cAMP dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein coupled receptor. This gene contains no introns in either its coding or untranslated sequences. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. Expression of the beta 2 Adrenergic Receptor has been reported in adipose, blood, brain, heart, lung, nose, pancreas, skeletal muscle, skin, and vessel. |
| 免疫原 | KLH conjugated synthetic peptide: human ADRB2 |
| 抗原种属 | Human |
| 基因名称 | ADRB2 |
| 基因ID | |
| 蛋白名称 | beta-2 adrenergic receptor |
| Uniprot ID | |
| 研究领域 | Ischemia / Reperfusion,Myocardial regeneration,GPCR |
| 功能 | Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine. |
| 分子量 | Theoretical: 46 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | store at -20°C |