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TSLP Protein, Human, Recombinant (R127A & R130S, His)

产品编号 TMPY-05220
TSLP Protein, Human, Recombinant (R127A & R130S, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.2 kDa and the accession number is Q969D9-1.
规格价格库存数量
100 μg¥ 3,130现货
200 μg¥ 5,5305日内发货
500 μg¥ 11,7205日内发货
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生物活性

生物活性
Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
产品描述
TSLP Protein, Human, Recombinant (R127A & R130S, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.2 kDa and the accession number is Q969D9-1.
种属
Human
表达系统
HEK293 Cells
标签C-His
蛋白编号Q969D9-1
别名
thymic stromal lymphopoietin
蛋白构建
A DNA sequence encoding the human TSLP (NP_149024.1) (Met1-Gln159, with mutation Arg 127 Ala, Arg 130 Ser) was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: Met 1
蛋白纯度
> 95 % as determined by SDS-PAGE.
TSLP Protein, Human, Recombinant (R127A & R130S, His)
分子量16.2 kDa (predicted)
内毒素< 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法
A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式In general, Lyophilized powders are shipping with blue ice.
研究背景
Thymic stromal lymphopoietin (TSLP) is an interleukin 7 (IL-7)-like cytokine originally characterized by its ability to promote the activation of B cells and dendritic cells (DCs). Thymic stromal lymphopoietin (TSLP) is a cytokine expressed by epithelial cells, including keratinocytes, and is important in allergic inflammation. Subsequent studies have shown that TSLP promotes T helper type 2 (TH2) cell responses associated with immunity to some helminth parasites and the pathogenesis of many inflammatory diseases, including atopic dermatitis and asthma. TSLP can promote TH2 cytokine-associated inflammation by directly promoting the effector functions of CD4+TH2 cells, basophils and other granulocyte populations while simultaneously limiting the expression of DC-derived proinflammatory cytokines and promoting regulatory T cell responses in peripheral tissues.

计算器

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  • 重组蛋白稀释 计算器
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