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Anti-CDNF Antibody (9J828) 是一种 Rabbit 抗体,靶向 CDNF。Anti-CDNF Antibody (9J828) 可用于 ELISA。
Anti-CDNF Antibody (9J828) 是一种 Rabbit 抗体,靶向 CDNF。Anti-CDNF Antibody (9J828) 可用于 ELISA。
产品描述 | Anti-CDNF Antibody (9J828) is a Rabbit antibody targeting CDNF. Anti-CDNF Antibody (9J828) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 9J828 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human CDNF / ARMETL1 (rh CDNF / ARMETL1; TMPY-00568; NP_001025125.2; Met1-Leu187). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Cerebral Dopamine Neurotrophic Factor (CDNF), also known as ARMETL1 (ARMET-like protein 1), is a secreted protein with eight conserved cysteine residues, predicting a unique protein fold and defining a new, evolutionarily conserved protein family. CDNF is a novel neurotrophic factor with strong trophic activity on dopaminergic neurons comparable to that of glial cell line-derived neurotrophic factor (GDNF). CDNF/ARMETL1 is a evolutionary conserved protein which can protect and restore the function of dopaminergic neurons in the rat model of Parkinson's disease, suggesting that CDNF might be beneficial for the treatment of Parkinson's disease. CDNF is widely expressed in neurons in several brain regions including cerebral cortex, hippocampus, substantia nigra, striatum and cerebellum. Human CDNF is glycosylated and secreted from transiently transfected cells. CDNF promotes the survival, growth, and function of dopamine-specific neurons and is expressed in brain regions that undergo cocaine-induced neuroplasticity. |
偶联 | Unconjugated |
免疫原 | Recombinant Human CDNF / ARMETL1 Protein (TMPY-00568) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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