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Anti-ACACA Antibody (2D514)
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产品编号 TMAC-00057
别名 Acetyl-Coenzyme A carboxylase alpha (ACC-alpha), Acetyl-CoA carboxylase 1, ACC1, ACACA, ACAC
Anti-ACACA Antibody (2D514) 是一种 Mouse 抗体，靶向 ACACA。Anti-ACACA Antibody (2D514) 可用于 WB,IP,IF。
Anti-ACACA Antibody (2D514)
Anti-ACACA Antibody (2D514)
还可以产品编号 TMAC-00057 别名 Acetyl-Coenzyme A carboxylase alpha (ACC-alpha), Acetyl-CoA carboxylase 1, ACC1, ACACA, ACAC
Anti-ACACA Antibody (2D514) 是一种 Mouse 抗体，靶向 ACACA。Anti-ACACA Antibody (2D514) 可用于 WB,IP,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,995 | 5日内发货 | |
| 100 μL | ¥ 2,990 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
化学信息
| 产品描述 | Anti-ACACA Antibody (2D514) is a Mouse antibody targeting ACACA. Anti-ACACA Antibody (2D514) can be used in WB,IP,IF. |
| 别名 | Acetyl-Coenzyme A carboxylase alpha (ACC-alpha), Acetyl-CoA carboxylase 1, ACC1, ACACA, ACAC |
| 交叉反应 | Human |
| 验证活性 | 1. Western blot analysis of ACCα expression in DU 145 (A) and Jurkat (B) whole cell lysates. |
| 应用 | |
| 推荐剂量 | WB: 1:100-1000; IP: 1-2 μg per 100-500 μg of total protein |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. Exercise diminishes the activity of acetyl-CoA carboxylase in human muscle. ACCα (ACC1) is the rate-limiting enzyme in the biogenesis of long-chain fatty acids, and ACCβ (ACC2) may control mitochondrial fatty acid oxidation. These two isoforms of ACC control the amount of fatty acids in the cells. The catalytic function of ACCα is regulated by phosphorylation (inactive) and dephosphorylation (active) of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA, which serve as the enzyme’s short-term regulatory mechanism. The gene encoding ACCα maps to human chromosome 17 and encodes a form of ACC, which is the major ACC in lipogenic tissues. The catalytic core of ACCβ is homologous to that of the ACCα, except for an additional peptide of about 150 amino acids at the N-terminus. |
| 偶联 | Unconjugated |
| 免疫原 | Peptide |
| Uniprot ID |
| 分子量 | Theoretical: 265 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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