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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-MASP1/MASP3 Polyclonal Antibody

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货号 TMAB-08624

Anti-MASP1/MASP3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 MASP1/MASP3。Anti-MASP1/MASP3 Polyclonal Antibody 可用于 WB。

Anti-MASP1/MASP3 Polyclonal Antibody

Anti-MASP1/MASP3 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-08624

Anti-MASP1/MASP3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 MASP1/MASP3。Anti-MASP1/MASP3 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-MASP1/MASP3 Polyclonal Antibody is a Rabbit antibody targeting MASP1/MASP3. Anti-MASP1/MASP3 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Dog,Pig,Cow,Rabbit)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted.
组织特异性Protein of the plasma which is primarily expressed by liver.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010]
抗原信息
免疫原
KLH conjugated synthetic peptide: human MASP
抗原种属
Human
基因名称
MASP1
基因ID
5648
蛋白名称
Mannan-binding lectin serine protease 1
Uniprot ID
P48740
功能
Functions in the lectin pathway of complement, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2. Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction. Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5.
化学信息
分子量Theoretical: 49/77 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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