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Anti-BAFF/TNFSF13B Antibody (7J925)
还可以产品编号 TMAY-00195
Anti-BAFF/TNFSF13B Antibody (7J925) 是一种 Rabbit 抗体，靶向 BAFF/TNFSF13B。Anti-BAFF/TNFSF13B Antibody (7J925) 可用于 WB。
Anti-BAFF/TNFSF13B Antibody (7J925)
Anti-BAFF/TNFSF13B Antibody (7J925)
还可以产品编号 TMAY-00195
Anti-BAFF/TNFSF13B Antibody (7J925) 是一种 Rabbit 抗体，靶向 BAFF/TNFSF13B。Anti-BAFF/TNFSF13B Antibody (7J925) 可用于 WB。
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产品介绍
生物活性
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抗原信息
| 产品描述 | Anti-BAFF/TNFSF13B Antibody (7J925) is a Rabbit antibody targeting BAFF/TNFSF13B. Anti-BAFF/TNFSF13B Antibody (7J925) can be used in WB. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 7J925 |
| 交叉反应 | Human |
| 验证活性 | Anti-BAFF rabbit monoclonal antibody at 1:500 dilution. -Lane A: HL60 Whole Cell Lysate. -Lane B: Jurkat Whole Cell Lysate. -Lane C: MOLT-4 Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. -Developed using the ECL technique. -Performed under reducing conditions. -Predicted band size:34 kDa. -Observed band size:35 kDa |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human BAFF/TNFSF13B (rh BAFF/TNFSF13B; TMPY-02775; Q9Y275-1; Ala134-Leu285). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | B lymphocyte stimulator (BLyS), also known as TNFSF13B, CD257 and BAFF, is a single-pass type II membrane protein, which belongs to the tumor necrosis factor family. BAFF is abundantly expressed in peripheral blood Leukocytes and is specifically expressed in monocytes and macrophages. BAFF is a cytokine and serves as a ligand for receptors TNFRSF13B (TACI), TNFRSF17 (BCMA), and TNFRSF13C (BAFFR). These receptors are a prominent factor in B cell differentiation, homeostasis, and selection. BLyS levels affect survival signals and selective apoptosis of autoantibody-producing B cells. Thus, it acts as a potent B cell activator and has been shown to play an important role in the proliferation and differentiation of B cells. Overexpression of BLyS in mice can lead to clinical and serological features of systemic lupus erythematosus (SLE) and Sjögren's syndrome (SS). BLyS is an attractive therapeutic target in human rheumatic diseases. The ability of BLyS to regulate both the size and repertoire of the peripheral B cell compartment raises the possibility that BLyS and antagonists thereof may form the basis of a therapeutic trichotomy. As an agonist, BLyS protein may enhance humoral immunity in congenital or acquired immunodeficiencies such as those resulting from viral infection or cancer therapy.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human BAFF/TNFSF13B Protein (TMPY-02775) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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