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Anti-IL-T4 Antibody (5V475) 是一种 Mouse 抗体,靶向 IL-T4。Anti-IL-T4 Antibody (5V475) 可用于 ELISA,FCM。
Anti-IL-T4 Antibody (5V475) 是一种 Mouse 抗体,靶向 IL-T4。Anti-IL-T4 Antibody (5V475) 可用于 ELISA,FCM。
产品描述 | Anti-IL-T4 Antibody (5V475) is a Mouse antibody targeting IL-T4. Anti-IL-T4 Antibody (5V475) can be used in ELISA,FCM. |
Ig Type | Monoclonal Mouse IgG2b |
克隆号 | 5V475 |
交叉反应 | Human |
验证活性 | Flow cytometric analysis of Human LILRB2(CD85d) expression on human whole blood monocytes. Cells were stained with purified anti-Human LILRB2(CD85d), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable monocytes. |
应用 | ELISA,FCM |
推荐剂量 | ELISA: 1:1000-1:2000; FCM: 1:25-1:100 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human LILRB2 / ILT4 / LIR-2 (rh LILRB2 / ILT4 / LIR-2; TMPY-03284; AAH36827.1; Met1-Val461). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | ILT4, also known as LILRB2, is a member of the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). ILT4 gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family. Multiple transcript variants encoding different isoforms have been found for the ILT4 gene. ILT4 is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. |
偶联 | Unconjugated |
其他可选修饰符 | APC/FITC/PE |
可提供抗体种类 | 4 |
免疫原 | Recombinant Human LILRB2 / ILT4 / LIR-2 Protein (TMPY-03284) |
抗原种属 | Human |
研究领域 | ITIM/ITAM Immunoreceptors and Related Molecules |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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