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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-ACTH Monoclonal Antibody (4Y745)

Synonyms: POMC, POC, OBAIRH, NPP, MSH, LPH, CLIP
货号 TMAT-0022 一键复制产品信息
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Anti-ACTH Monoclonal Antibody (4Y745) 是一种 Mouse 抗体，靶向 ACTH。Anti-ACTH Monoclonal Antibody (4Y745) 可用于 IHC,FCM。

Anti-ACTH Monoclonal Antibody (4Y745)

一键复制产品信息
Rating icon 还可以
货号 TMAT-0022

别名 POMC, POC, OBAIRH, NPP, MSH, LPH, CLIP

Anti-ACTH Monoclonal Antibody (4Y745) 是一种 Mouse 抗体，靶向 ACTH。Anti-ACTH Monoclonal Antibody (4Y745) 可用于 IHC,FCM。

Anti-ACTH Monoclonal Antibody (4Y745)
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产品介绍

生物活性
产品描述
Anti-ACTH Monoclonal Antibody (4Y745) is a Mouse antibody targeting ACTH. Anti-ACTH Monoclonal Antibody (4Y745) can be used in IHC,FCM.
别名
POMC, POC, OBAIRH, NPP, MSH, LPH, CLIP
Ig Type
IgG1
克隆号
4Y745
反应种属
Human
应用IHCFCM
推荐剂量
IHC: 1/200-1/1000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/ml
研究背景This gene encodes a preproprotein that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the preproprotein and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. The antimicrobial melanotropin alpha peptide exhibits antibacterial and antifungal activity. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human ACTH expressed in E. Coli.
抗原种属
Human
基因名称
POMC
基因ID
5443
蛋白名称
Pro-opiomelanocortin
Uniprot ID
P01189
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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